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184 items found for "double mutant cycle analysis"
- Transmembrane domains of GPCR dimers – a novel hot spot for drug discovery
A more in-depth analysis of the functional specificity of transmembrane peptides will provide a better
- CCL25/CCR9 interaction promotes the malignant behavior of salivary adenoid cystic carcinoma via...
Methods Immunohistochemistry staining and RT–qPCR analyses were performed to detect the correlation
- 📰 GPCR Weekly News, December 18 to 31, 2023
numbering residues and a proposal for naming structural motifs and subfamilies Comparative genomic analysis
- 📰 GPCR Weekly News, April 8 to 14, 2024
Samuel Hoare on Advanced data analysis for GPCR pharmacology, which will be held on Thursdays between
- Structural landscape of the Chemokine Receptor system
A recent comparative analysis study of all structures of CKRs characterizes the molecular recognition The structural analysis of CCR1 demonstrates how the interaction or absence of interaction with a specific
- 📰 GPCR Weekly News, May 29 to June 4, 2023
Transcriptomic analysis of human cytomegalovirus to survey the indirect effects on renal transplant recipients
- Regulators of G-protein signaling: essential players in GPCR signaling
The interaction between RGS proteins and GPCRs is highly specific and tightly regulated; mutations in
- Biphasic activation of β-arrestin 1 upon interaction with a GPCR revealed by methyl-TROSY NMR
Our NMR analyses demonstrated that while the C tail-mediated interaction alone induces partial activation
- Latrophilin-1 drives neuron morphogenesis and shapes chemo- and mechanosensation-dependent ...
Detailed expression and RNA-Seq analyses revealed specific LAT-1-positive neurons and first insights
- Activation of GPR183 by 7 α,25-Dihydroxycholesterol Induces Behavioral Hypersensitivity through...
Non-biased transcriptomic analyses of dorsal-horn spinal cord (DH-SC) tissues harvested at the time of
- Feeder or trigger – CCR2 as a scavenger and regulator of cell migration
This study provides a comprehensive analysis of CCR2 scavenging role however to fully understand the
- 📰 GPCR Weekly News - January 2 to 8, 2023
Structural and Molecular Insights into GPCR Function Structural and functional analyses of a GPCR-inhibited
- 📰 GPCR Weekly News, March 20 to 26, 2023
Lead (depending on experience) with Structural Bioinformatics Expertise Scientist Corporate Strategy Analyst
- 📰 GPCR Weekly News, February 5 to 11, 2024
Sequential Design of G Protein-Coupled Receptors Using Protein Language Models Scaling up Functional Analyses
- Chemokine receptor-targeted drug discovery: progress and challenges
of mycosis fungoides or Sézary syndrome in adults which are subtypes of cutaneous T-cell lymphoma (CTCL
- Glyco-sulfo hotspots in the chemokine receptor system
In silico analyses done in this study with the NetOGlyc 4.0 prediction algorithm (Steentoft C et al.