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research assistant at the Victor Chang Cardiac Research Institute where he investigated the orphan G protein-coupled

Alfred Gillman , co-recipient of the 1994 Nobel Prize in Physiology or Medicine for their discovery of G-proteins

His interests are in receptor pharmacology, allosteric protein function, and drug discovery. Dr.

multiple areas of GPCR research such as sequence alignments, generic numbering systems, structure data, G protein

Fung has spent significant time in the industry studying membrane proteins, antibodies, and HTS methods

his group reported the first in vivo GPCR interactome, revealing an important number of new potential proteins

Finally, we identified that G protein-coupled receptor (GPCR)-phospholipase C (PLC)-inositol trisphosphate G protein-coupled receptor (GPCR)-phospholipase C (PLC)-inositol trisphosphate receptor (IP3R)-SOC signaling

He adapts interdisciplinary approaches (synthesis, modeling, pharmacology) to study G protein-coupled

can overcome these obstacles by producing high-quality antibodies that more accurately mimic natural protein

His lab has worked on building large-scale ways of empirically exploring questions in protein biochemistry

Aaron is currently the Chief Scientific Officer and VP of Protein Engineering. Aaron has a proven track record as a biologics leader as he led teams to discover and develop novel first-in-class

University of Nottingham in 2006, where he is now Associate Professor, establishing a lab focused on G protein-coupled

Francisco with Professor Mark von Zastrow where she identified novel core cellular machinery critical for G protein-coupled

Molecular Medicine and Neuroscience at the University of Ottawa as a Postdoctoral Fellow to explore novel G protein-coupled

chemokine and metabolite GPCRs in personalized cancer therapy Published date September 12, 2024 Abstract "G protein-coupled

Senior Principal Research Fellow and Director, ARC Centre for Cryo-electron Microscopy of Membrane Proteins

reviewed the standard nomenclature for chemokine receptors that are categorized into a large subgroup of G protein–coupled

Philadelphia, PA, for his postdoctoral training in Jeff Benovic’s laboratory studying the regulation of G protein-coupled

Prasad Pydi obtained his Ph.D. from the University of Manitoba – Canada, where he was introduced to G protein-coupled

Allosteric Modulation and Drug Discovery Yamina and Arthur delved into the complexities of protein-protein They discussed various modulatory elements, such as RAMPs, G proteins, and GRKs, with Arthur recounting

NTF Release Sensor Approach for Drug Discovery for Human Adhesion GPCRs Stephanie Häfner Abstract "G Protein-coupled receptors (GPCRs) are common drug targets, yet no approved drugs exist for the Adhesion G Protein-coupled been successfully used internally to identify biased small molecule negative allosteric modulators for protease-activated Salinas "I am currently part of a dynamic research team dedicated to advancing the understanding of G protein-coupled

Uppsala University in Sweden where he worked on the bioinformatic identification of 24 novel human G protein-coupled

He is the Research director at INSERM with a specific interest in G protein-coupled receptors by developing

elevated in disease settings, where the largest group of CC-chemokines are the macrophage inflammatory proteins

development Published date June 14, 2024 Abstract "P2Y12 receptor (P2Y12R) is an adenosine-activated G protein-coupled

Molecular Medicine and Neuroscience at the University of Ottawa as a Postdoctoral Fellow to explore novel G protein-coupled

Xu et al. identified the mammalian neurokinin 3 receptor (TACR3), a homolog of the G protein-coupled

work, during which time I thoroughly reviewed the literature on the melanocortin receptor accessory protein then undertook my first project where I demonstrated that MRAP2 regulates the signaling of multiple G protein-coupled