Search Results
216 items found for "Lauren T May"
- Multifunctional role of GPCR signaling in epithelial tube formation
We also report on unexpected Fog-independent roles for Smog in maintaining epithelial integrity and organizing
- Fly casting with ligand sliding and orientational selection supporting complex formation of a GPCR..
free-energy landscape of the ligand-receptor binding by searching large-scale motions accompanied with stable maintenance
- To probe the activation mechanism of the Delta opioid receptor by an agonist ADL5859 started from...
While the receptor with the crystal ligand (i.e. antagonist naltrindole) maintained the inactive conformation
- A broad look into the future of systemic sclerosis
transcriptional programmes will be introduced as well as epigenetic modifications, which are pivotal to maintain from SSc patients exhibit a specific signalling and reactivate developmental pathways and stem cell maintenance
- FSH and bone: Comparison between males with central versus primary hypogonadism
effect of follicle-stimulating hormone (FSH) on the skeletal metabolism, but results of human studies mainly
- PAR-Induced Harnessing of EZH2 to β-Catenin: Implications for Colorectal Cancer
array of physiological and disease functions, yet knowledge of their role in colon cancer stem cell maintenance
- Identification of hub genes in the subacute spinal cord injury in rats
Subacute SCI is mainly characterized by neuronal apoptosis, axonal demyelination, Wallerian degeneration
- Immunomodulatory Role of Neuropeptides in the Cornea
This review focuses on the role of neuropeptides in maintaining the homeostasis of the ocular surface
- Endocannabinoid System in the Neuroendocrine Response to Lipopolysaccharide-induced Immune Challenge
It is well known that immune challenges, such as exposure to lipopolysaccharide, the main component of
- Dynamics of tumor-associated macrophages in a quantitative systems pharmacology model of...
proper calibration, the model captures the macrophage heterogeneity in the tumor microenvironment while maintaining
- Professor Charlotte Deane Joins Exscientia as Chief Scientist of Biologics AI
She will maintain both of these roles, in addition to her role at Exscientia .
- ChemoCentryx Announces EU Approval of TAVNEOS® (avacopan) for the Treatment of ANCA-Associated ...
patients with severe, active granulomatosis polyangiitis (GPA) or microscopic polyangiitis (MPA), the two main
- Murine bone marrow macrophages and human monocytes do not express atypical chemokine receptor 1
suggesting that macrophage ACKR1 engages its non-cognate ligand CD82 on hematopoietic stem cells (HSCs) to maintain
- Karuna Therapeutics Announces Positive Results from Phase 3 EMERGENT-2 Trial of KarXT in...
statistically significant reduction of symptoms, as assessed by PANSS total score, starting at Week 2 and maintained
- Discovery of 3(2-aminoethyl)-thiazolidine-2,4-diones as a novel chemotype of sigma-1 receptor ligand
August 2022 "Abstract Sigma receptor is a transmembrane non-GPCR protein expressed mainly in the endoplasmic
- Rhodopsin as a Molecular Target to Mitigate Retinitis Pigmentosa
These disorders are mainly related to the abnormalities in the rod G protein-coupled receptor (GPCR),
- Allosteric Effect of Nanobody Binding on Ligand-Specific Active States of the β2 Adrenergic Receptor
modulated by a full agonist, BI167107, and a G-protein-biased partial agonist, salmeterol, involving mainly
- Lysophosphatidic Acid and Several Neurotransmitters Converge on Rho-Kinase 2 Signaling to Manage...
knockdown both depressed AMPAergic, inspiratory-related discharge activity of adult HMNs in vivo , which mainly
- Chronic itch: emerging treatments following new research concepts
Currently, inhibitors of IL-31, IL-4/13, NK1 receptors, opioids and cannabinoids, JAK, PDE4 or TRP are the main
- TLR4 biased small molecule modulators
Currently, attention was mainly paid to biased signaling modulators targeting G protein-coupled receptors