and stabilizing IGF1R, and suggests that it may serve as a valuable prognostic factor and potential therapeutic

the current status of ligand development targeting LPA receptors to modulate LPA signaling and their therapeutic

The scavenging function of CKRs should be considered when evaluating the safety and therapeutic efficacy

synaptic depression in dorsolateral striatum of adult male mice Methods & Updates in GPCR Research RNA therapeutics

indicated by the fact that about 40% of all drugs currently used in clinical practice mediate their therapeutic

advancing the understanding of the effects of genetic mutations on GPCR function and provide a proof of therapeutic

cognate positions across GPCR paralogs opens a window into cancer mechanisms and potential approaches to therapeutics

challenges is crucial to fully harness AI's potential in accelerating drug discovery and optimizing therapeutic

puzzles and underscores the importance of understanding cellular processes at the molecular level for therapeutic

Tethered Ligands that Target the µ-Opioid Receptor Design and Synthesis of Novel GPR139 Agonists with Therapeutic

Hopkins, Exscientia’s founder and CEO was elected a Fellow of the Academy of Medical Sciences Structure Therapeutics

Enter into Multitarget Antibody Discovery Research Collaboration Neurocrine Biosciences and Voyager Therapeutics

way for understanding the CBD pharmacology at a molecular level and aid in harnessing its potential therapeutic

Subject in Phase 1 Trial with HTL0033744, an EP4 Agonist for Inflammatory Bowel Disease (IBD) Domain Therapeutics

implications for drug development, as targeting these non-cognate interactions could lead to novel therapeutic

understanding how serotonin receptors, one of the largest subfamilies of class A GPCRs and potential therapeutic

Orbit Discovery and Endevica Bio enter multi-target collaboration to advance development of cachexia therapeutics

modulating autophagy and the CDKN1B-CDK2-CCNE1-E2F1 axis and indicate that ARRB1 may be a potential therapeutic

Foundation is awarding DKK 174 million in grants to seven ‘mind-bending’ research collaborations GPCR Therapeutics

revolution of biased signalling of GPCRs comes the possibility of designing drugs that selectively activate therapeutically analyzing drug-target interactions and disease pathways, AI can identify potential candidates that may have therapeutic

the atomic-level quaternary structure of short-lived GPCR oligomers in live cells Industry News Confo Therapeutics

potential use of Opn5 and its homologs Industry News The Leading GPCR Company in Immuno-Oncology, Domain Therapeutics

GPCRs remain one of the most prolific and fertile therapeutic drug targets.

Muscarinic Agonist Candidates in Phase 1 Clinical Studies AbbVie to acquire neuroscience drugmaker Cerevel Therapeutics

GPCR Binders, Drugs, and more Novel targets for potential therapeutic use in Diabetes mellitus.

Jefferies Healthcare Conference in London Sosei Heptares and Kallyope Nominate First GPCR Target for Therapeutic

Domain Therapeutics was nominated for the Trophée de l'Innovation Technologique (Technological Innovation

Fourth Quarter and Fiscal 2023 Financial Results and Provides Financial Expectations for 2024 Domain Therapeutics