Search Results
362 items found for "Vivian G Oehler"
- Production of human A2AAR in lipid nanodiscs for 19F-NMR and single-molecule fluorescence...
October 2022 "We describe production of the human A2A adenosine receptor (A2AAR), a class A G protein-coupled
- Specific Functions of Melanocortin 3 Receptor (MC3R)
October 2022 "Melanocortin 3 receptor (MC3R) is a G-protein coupled receptor (GPCR) that is defined
- Transformative GPCR Insights: Unleash New Horizons in Science | Sep 9 - 15, 2024
GPCR Event Spotlight Discovery on Target’s 19th Annual GPCR-Based Drug Discovery Targeting G Protein-Coupled Postdoctoral Position Postdoctoral research position Adhesion GPCRs Loss of cardiomyocyte-specific Adhesion G Neuroscience Gain control of sensory input across polysynaptic circuitries in mouse visual cortex by a single G
- MSX-122: Is an effective small molecule CXCR4 antagonist in cancer therapy?
C-X-C motif chemokine receptor 4 (CXCR4), a G-protein-coupled receptor (GPCR), has one identified natural
- Production of human A2AAR in lipid nanodiscs for 19F-NMR and single-molecule fluorescence...
fluorescence spectroscopy "We describe production of the human A2A adenosine receptor (A2AAR), a class A G
- Angiotensin-(1-7) improves cognitive function and reduces inflammation in mice following mild trauma
Angiotensin 1-7 (Ang-1-7), an endogenous peptide, acts at the G protein coupled MAS1 receptors (MASR)
- GRK3 is a poor prognosticator and serves as a therapeutic target in advanced gastric adenocarcinoma
September 2022 "Background G protein-coupled receptor (GPCR) is the most targeted protein family by
- Verily links up with Sosei Heptares for GPCR drug discovery
January 2022 "G-protein-coupled receptors’ star has been on the rise in biotech in recent years as researchers
- Septerna emerges with $100M to spark 'second golden age' of prolific drug target GPCR with ...
with pioneer as co-founder "J an 27, 2022 07:00am Septerna wants to spark a second golden age in G-protein-coupled
- Mechanism of enhanced sensitivity of mutated β-adrenergic-like octopamine receptor to amitraz in...
Previous assays verified that a typical G protein-coupled receptor, β-adrenergic-like octopamine receptor
- GRK2 selectively attenuates the neutrophil NADPH-oxidase response triggered by β-arrestin recruiting
avoid a prolonged pro-inflammatory neutrophil response, signaling downstream of an agonist-activated G
- Opioid Ligands Addressing Unconventional Binding Sites and More Than One Opioid Receptor Subtype
August 2022 "Opioid receptors (ORs) represent one of the most significant groups of G-protein coupled
- Emerging approaches for decoding neuropeptide transmission
includes their post-translational processing, release from dense core vesicles, and ability to activate G-protein-coupled
- Domain Therapeutics Raises $42m Series A Financing
biopharmaceutical company specializing in the research and development of innovative drugs targeting G
- GPCR Therapeutics Expands Scientific Advisory Board
international biopharmaceutical company with an innovative approach to drug discovery based on targeting G
- Nanobodies: New Dimensions in GPCR Signaling Research
Nanobodies to Study G Protein-Coupled Receptor Structure and Function. G., Choi, H. J., Fung, J. J., Pardon, E., Casarosa, P., Chae, P. S., Devree, B. T., Rosenbaum, D. Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor.
- Developing the Cannabinoid Receptor 2 (CB2) pharmacopoeia: past, present, and future
October 2022 "Cannabinoid Receptor 2 (CB2) is a G protein-coupled receptor (GPCR) with considerable,
- Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency to mTORC1
lysosomal proteomes, we identified lysosomal cholesterol signaling (LYCHOS, previously annotated as G
- 📰 GPCR Weekly News, May 15 to 21, 2023
FSLLRY-NH2, a protease-activated receptor 2 (PAR2) antagonist, activates mas-related G protein-coupled ACE2 Activation by Tripeptide IRW (Ile-Arg-Trp) Depends on the G Protein-Coupled Receptor 30 Signaling
- Developing the Cannabinoid Receptor 2 (CB2) pharmacopeia: past, present, and future
August 2022 "Cannabinoid Receptor 2 (CB2) is a G protein-coupled receptor (GPCR) with considerable, though
- Posttranslational modifications in GPCR internalization
August 2022 "G protein-coupled receptors (GPCRs) are the largest family of membrane receptors that serve
- Molecular basis for ligand modulation of the cannabinoid CB 1 receptor
August 2022 "The cannabinoid CB1 receptor is the most abundant G protein coupled receptor (GPCR)
- 📰 GPCR Weekly News, April 17 to 23, 2023
Regulation of the pro-inflammatory G protein-coupled receptor GPR84. GPCRs in Neuroscience G protein coupled receptors as targets for transformative neuropsychiatric therapeutics
- Chemerin Forms: Their Generation and Activity
Chemerin can signal via two G protein-coupled receptors, chem1 and chem2, as well as be bound to a third
- Allosteric Effect of Nanobody Binding on Ligand-Specific Active States of the β2 Adrenergic Receptor
Nanobody binding stabilizes G-protein-coupled receptors (GPCR) in a fully active state and modulates binding site and the extracellular domains in conformations modulated by a full agonist, BI167107, and a G-protein-biased
- Adenosine receptor signalling in Alzheimer's disease
Emerging evidence suggests adenosine G protein-coupled receptors (GPCRs) are promising therapeutic targets
- High hedgehog signaling is transduced by a multikinase-dependent switch controlling the...
multikinase-dependent switch controlling the apico-basal distribution of the GPCR smoothened "The oncogenic G-protein-coupled
- Adenosine receptor signalling in Alzheimer's disease
Emerging evidence suggests adenosine G protein-coupled receptors (GPCRs) are promising therapeutic targets