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254 items found for "drug repurposing"
- Opposite Effects of Src Family Kinases on YAP and ERK Activation in Pancreatic Cancer Cells: Implications for Targeted Therapy
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- Deciphering a GPCR-lncRNA-miRNA Nexus: Identification of an Aberrant Therapeutic Target in Ovarian Cancer
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- The β2-adrenergic receptor associates with CXCR4 multimers in human cancer cells
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- Spliceosome mutations are associated with clinical response in a phase 1b/2 study of the PLK1 inhibitor onvansertib in combination with decitabine in relapsed or refractory acute myeloid leukemia
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- SSTR2 positively associates with EGFR and predicts poor prognosis in nasopharyngeal carcinoma
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- Ultrasensitive dose-response for asbestos cancer risk implied by new inflammation-mutation model
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- G protein-coupled receptors: A target for microbial metabolites and a mechanistic link to microbiome-immune-brain interactions
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- A disturbed metabolite-GPCR axis is associated with microbial dysbiosis in IBD patients: Potential role of GPR109A in macrophages
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- Lactate receptor GPR81 drives breast cancer growth and invasiveness through regulation of ECM properties and Notch ligand DLL4
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- GPR97 depletion aggravates imiquimod-induced psoriasis pathogenesis via amplifying IL-23/IL-17 axis signal pathway
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- Wnt pathway inhibition with the porcupine inhibitor LGK974 decreases trabecular bone but not fibrosis in a murine model with fibrotic bone
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- Ovarian cancer G protein-coupled receptor 1 (OGR1) deficiency exacerbates crystal deposition and kidney injury in oxalate nephropathy in female mice
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- Exploiting frequent and specific expression of PRL3 in pediatric solid tumors for first-in-child use of PRL3-zumab humanized antibody
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- Esophageal and gastric cancer incidence trends in Golestan, Iran: An age-period-cohort analysis 2004 to 2018
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- Glucose and HODEs regulate Aspergillus ochraceus quorum sensing through the GprC-AcyA pathway
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- Clinical, pathophysiologic, genetic and therapeutic progress in Primary Bilateral Macronodular Adrenal Hyperplasia
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- Drosophila cytokine GBP2 exerts immune responses and regulates GBP1 expression through GPCR receptor Mthl10
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- Identification of a G-protein coupled receptor-related gene signature through bioinformatics analysis to construct a risk model for ovarian cancer prognosis
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- Molecular docking and dynamics simulation studies uncover the host-pathogen protein-protein interactions in Penaeus vannamei and Vibrio parahaemolyticus
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- Prediction of survival and immunotherapy response by the combined classifier of G protein-coupled receptors and tumor microenvironment in melanoma
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- Proteogenomic landscape and clinical characterization of GH-producing pituitary adenomas/somatotroph pituitary neuroendocrine tumors
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- Identification of S1PR4 as an immune modulator for favorable prognosis in HNSCC through machine learning
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- Classified News | Dr. GPCR Ecosystem
GPCR Route 66+ project Read More October 1, 2022 GPCRs: Signal Transduction Read More GPCR Binders, Drugs
- Context-dependent ciliary regulation of hedgehog pathway repression in tissue morphogenesis
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- Stimulation of ectopically expressed muscarinic receptors induces IFN-γ but suppresses IL-2 production by inhibiting activation of pAKT pathways in primary T cells
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- Ep 82 with Dr. Lauren M. Slosky
within the University of Minnesota’s Medical School to advance research and treatment in the field of drug
- Respiratory infections predominate after day 100 following B-cell maturation antigen-directed CAR T-cell therapy
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- Colorectal cancer incidence trends in Golestan, Iran: An age-period-cohort analysis 2004-2018
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