Search Results
274 items found for "protein expression"
- Ep 73 with Dr. Aylin Hanyaloglu
Francisco with Professor Mark von Zastrow where she identified novel core cellular machinery critical for G protein-coupled
- Ep 93 with Dr. Sri Kosuri
His lab has worked on building large-scale ways of empirically exploring questions in protein biochemistry
- Ep 56 with Dr. Adriano Marchese
Philadelphia, PA, for his postdoctoral training in Jeff Benovic’s laboratory studying the regulation of G protein-coupled
- Ep 62 with Dr. Sai Prasad Pydi
Prasad Pydi obtained his Ph.D. from the University of Manitoba – Canada, where he was introduced to G protein-coupled
- Ep 126 with Dr. Françoise Bachelerie
reviewed the standard nomenclature for chemokine receptors that are categorized into a large subgroup of G protein–coupled
- Session III | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
NTF Release Sensor Approach for Drug Discovery for Human Adhesion GPCRs Stephanie Häfner Abstract "G Protein-coupled receptors (GPCRs) are common drug targets, yet no approved drugs exist for the Adhesion G Protein-coupled been successfully used internally to identify biased small molecule negative allosteric modulators for protease-activated Salinas "I am currently part of a dynamic research team dedicated to advancing the understanding of G protein-coupled
- Ep 152 with Dr Arthur Christopoulos
Allosteric Modulation and Drug Discovery Yamina and Arthur delved into the complexities of protein-protein They discussed various modulatory elements, such as RAMPs, G proteins, and GRKs, with Arthur recounting
- A positive Allosteric Modulator of M1 Acetylcholine Receptors Improves Cognitive Deficits in Male and Female Alzheimer’s Mice
Molecular Medicine and Neuroscience at the University of Ottawa as a Postdoctoral Fellow to explore novel G protein-coupled
- Ep 45 with Dr Ralf Jockers
He is the Research director at INSERM with a specific interest in G protein-coupled receptors by developing
- Ep 33 with Dr. David E. Gloriam
Uppsala University in Sweden where he worked on the bioinformatic identification of 24 novel human G protein-coupled
- Role and recent progress of P2Y12 receptor in cancer development
development Published date June 14, 2024 Abstract "P2Y12 receptor (P2Y12R) is an adenosine-activated G protein-coupled
- Chemokine N-terminal-derived peptides differentially regulate signaling by the receptors CCR1 and CCR5
elevated in disease settings, where the largest group of CC-chemokines are the macrophage inflammatory proteins
- Ep 150 with Dr GPCR Team
GPCR, an ecosystem designed to bring together stakeholders interested in using G-Protein Coupled Receptors Associate at IQVIA and regulatory officer at the Food and Drug Authority (FDA) in Ghana, John has a proven passion for molecular pharmacology, his research focuses on elucidating the molecular basis of membrane protein
- Ep 140 with Dr Alix A J Rouault
work, during which time I thoroughly reviewed the literature on the melanocortin receptor accessory protein then undertook my first project where I demonstrated that MRAP2 regulates the signaling of multiple G protein-coupled
- Ep 142 with Dr Claudia Stäubert
received my degree in biochemistry from Leipzig University (Germany) being already fascinated by G protein-coupled Yamina expressed interest in attending a meeting about GPCRs and metabolism in the UK, but was unsure Yamina expressed interest in learning more about this topic as she realized her lack of knowledge on
- Ep 65 with Dr. Sudarshan Rajagopal
identifying novel signal transduction mechanisms of GPCRs, such as the formation of complexes between G proteins
- High Metabolite Concentrations in Portal Venous Blood as a Possible Mechanism for Microbiota Effects on the Immune System, and Western Diseases
Deficiency of SCFA would lead to pro-inflammatory immune cell skewing through insufficient G-protein
- Ep 90 with Dr. Nariman Balenga
I was fascinated by the multitude of processes that are regulated/dysregulated by GPCRs and RGS proteins A fungal serine protease allergen with GPCR-modulating features was discovered as a new biomarker and
- Targeting adenosine signaling for immuno-oncology
Date & Time Friday, November 3rd / 4:35 PM Abstract "Adenosine (ADO) signaling through A2A and A2B G protein-coupled
- Ep 98 with Dr. GPCR Team
GPCR, an ecosystem designed to bring together stakeholders interested in using G-Protein Coupled Receptors
- Applying Pharmacology to Drug Discovery
My interests are in receptor theory, pharmacology applied to drug discovery and allosteric protein function
- CCR7 acts as both a sensor and a sink for CCL19 to coordinate collective leukocyte migration
By combining experimental data with theory on leukocyte chemotaxis guided by the G protein-coupled receptor
- GPCRs and fibroblast heterogeneity in fibroblast-associated diseases
fibroblast heterogeneity in fibroblast-associated diseases Published date August 1, 2023 Abstract "G protein-coupled
- Biochemical Mechanisms Underlying Location Bias in GPCR Signaling
identifying novel signal transduction mechanisms of GPCRs, such as the formation of complexes between G proteins
- Inhibition of Relaxin Autocrine Signaling Confers Therapeutic Vulnerability in Ovarian Cancer
The adapter protein 3BP2 is mutated in Cherubism.
- Principles of Pharmacology in Drug Discovery I
My interests are in receptor theory, pharmacology applied to drug discovery and allosteric protein function
- Plenary Lecture | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
for AGPCR24 Attendees About Jin-Peng Sun "Since starting my laboratory in 2011, I has focused on G protein For arrestin mediated biased signaling, we have proposed the “flute model” and “poly proline region docking
- Gi/o GPCRs drive the formation of actin-rich tunneling nanotubes in cancer cells via a Gβγ/PKCα/FARP1/Cdc42 axis
Cdc42 axis Published date June 26, 2023 Abstract "The functional association between stimulation of G-protein