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GPCR, an ecosystem designed to bring together stakeholders interested in using G-Protein Coupled Receptors Associate at IQVIA and regulatory officer at the Food and Drug Authority (FDA) in Ghana, John has a proven passion for molecular pharmacology, his research focuses on elucidating the molecular basis of membrane protein

I was fascinated by the multitude of processes that are regulated/dysregulated by GPCRs and RGS proteins A fungal serine protease allergen with GPCR-modulating features was discovered as a new biomarker and

GPCR, an ecosystem designed to bring together stakeholders interested in using G-Protein Coupled Receptors

identifying novel signal transduction mechanisms of GPCRs, such as the formation of complexes between G proteins

-bb1, Oprm1, Zfhx2, Gpr83, and Chrm2) were enriched in pathways related to inhibitory Gi-mediated G protein-coupled Progressive neuroinflammation spreads after injury, and neurotransmission through Gi-mediated G protein-coupled

human GPRC5D homodimer Published date June 19, 2024 Abstract "GPRC5D is an atypical Class C orphan G protein-coupled

regulate a wide spectrum of endocrine tumors Published date September 23, 2024 Abstract "Aberrant G-protein

Date & Time Friday, November 3rd / 4:35 PM Abstract "Adenosine (ADO) signaling through A2A and A2B G protein-coupled

Deficiency of SCFA would lead to pro-inflammatory immune cell skewing through insufficient G-protein

Inflammatory Diseases Published date April 20, 2023 Abstract " The CC chemokine receptor 6 (CCR6) is a G protein-coupled

My interests are in receptor theory, pharmacology applied to drug discovery and allosteric protein function

P2Y-like receptor to its role in cancer progression Published date December 6, 2024 Abstract "GPR87 is a G protein-coupled

By combining experimental data with theory on leukocyte chemotaxis guided by the G protein-coupled receptor

Here, we demonstrated that the neutrophil-expressed G-protein-coupled receptor (GPCR) Mrgpra1 is a negative

Chandra Jena, Daniel P Flaherty, Valerie P O'Brien, Val J Watts Tags Adenylyl Cyclase , Cancer , G protein

fibroblast heterogeneity in fibroblast-associated diseases Published date August 1, 2023 Abstract "G protein-coupled

migration and autophagy of hepatocellular carcinoma cells in vitro Published date June 26, 2023 Abstract "G protein-coupled Previous studies have indicated that GPR50 could protect against breast cancer development and decrease

identifying novel signal transduction mechanisms of GPCRs, such as the formation of complexes between G proteins

Here, we demonstrate that CB2, a G-protein-coupled receptor (GPCR) and member of the endocannabinoid Our results show that CB2 stimulation of ILC2s protects against insulin-resistance onset, ameliorates

Among other projects, I studied the role of β-arrestin in G protein trafficking, the impact of GPCR ubiquitination early tasks at Michelle’s lab, which involved creating stable cell lines and identifying potential protein the potential of multiplexing assays in expanding the scope of scientific exploration and finding new protein

The adapter protein 3BP2 is mutated in Cherubism.

feed-forward activation of the SK1-S1P1 signaling axis Published date August 15, 2023 Abstract "The G protein-coupled

mitoxantrone in untreated AML Published date September 12, 2023 Abstract "CC chemokine receptor-3 (hCCR3), a G protein-coupled

G-protein-coupled receptor class C group 5 member D (GPRC5D), an orphan GPCR predominantly expressed

dynamics in the mesenchymal transition of glioblastoma Published date November 19, 2023 Abstract "G protein-coupled Thus, based on transcriptomic, proteomic, and phosphoproteomic differential expression data of GPR56

characterized by a unique expression profile of ion channels, GPCR signaling molecules, synaptic vesicle cycle proteins

My interests are in receptor theory, pharmacology applied to drug discovery and allosteric protein function

August 29, 2024 Abstract "The growth hormone-releasing hormone receptor (GHRHR) belongs to Class B1 of G protein-coupled