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329 items found for "receptor binding"

  • GPR15 expressed in T lymphocytes from RA patients is involved in leukocyte chemotaxis to the synovium

    GPR15 is a G protein-coupled receptor (GPCR) located on chromosome 3 and has similarity in its sequence with chemokine receptors. GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders

  • A disturbed metabolite-GPCR axis is associated with microbial dysbiosis in IBD patients: Potential role of GPR109A in macrophages

    In this scenario, metabolite-sensing G-protein coupled receptors (GPCRs), involved in several biological The role of GPR109A was studied in depth and increased expression of this receptor was detected in epithelial GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders

  • GPR97 depletion aggravates imiquimod-induced psoriasis pathogenesis via amplifying IL-23/IL-17 axis signal pathway

    This autoimmune loop in psoriasis pathogenesis is influenced by G protein-coupled receptor (GPCR) signalling Role of GPR97 is indispensable and this adhesion receptor may affect immune cell enrichment and function GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders

  • Genetic Deletion of Atypical VGLUT3 Rescues Huntington’s Disease Phenotype and Neurodegeneration in zQ175 Mice

    / 2:10 PM About Karim Ibrahim "A postdoctoral researcher, interested in studying G-protein coupled receptors

  • NPFF stimulates human ovarian cancer cell invasion by upregulating MMP-9 via ERK1/2 signaling

    NPFF regulates a variety of physiological functions by binding to a G protein-coupled receptor (GPCR) GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders

  • "Have a nice weekend, and I'll see you tomorrow!": RAMP-interacting GPCR Pathways

    With a special emphasis on G protein coupled receptors and receptor activity modifying proteins in vascular

  • Ep 54 with Dr. JoAnn Trejo

    thorough and mechanistic understanding of processes that control cell signaling by protease-activated receptors Her laboratory is the recognized expert on protease-activated receptors, particularly PAR1, and over

  • Ep 151 with Dr GPCR Board

    GPCR, an ecosystem designed to bring together stakeholders interested in using G-Protein Coupled Receptors Her work focused on chemokine receptors, members of the GPCR family that control cell movement in the I am a recent convert and strong advocate for integrating mindfulness and mental wellbeing into demanding thorough and mechanistic understanding of processes that control cell signaling by protease-activated receptors Her laboratory is the recognized expert on protease-activated receptors, particularly PAR1, and over

  • Ep 60 with Dr. Josephine (Pina) Cardarelli

    discover and develop highly effective cancer therapeutics by targeting heteromers of G protein-coupled receptors At Medarex, she initiated and identified the lead mAb for the type I interferon-alpha receptor project extensive experience working with Biologics, and Antibody Drug Conjugates as well as experience in IND

  • Ep 24 with Dr. Masha Niv

    Her work focuses on both sweet and bitter taste receptor GPCRs and her lab established the BitterDB .

  • Ep 77 with Martin Audet

    Pharmacology of Sherbrooke and is an emerging leader in the structural biology of G Protein-Coupled Receptors

  • Ep 97 with Robert Laprairie

    The focus of his research is the molecular pharmacology of cannabinoids and cannabinoid receptors.

  • Ep 08 with Dr. Graciela Pineyro

    She has done extensive work on the molecular pharmacology of opioid receptors and is currently focusing

  • Unbiased multitissue transcriptomic analysis reveals complex neuroendocrine regulatory networks mediated by spinal cord injury-induced immunodeficiency

    Zfhx2, Gpr83, and Chrm2) were enriched in pathways related to inhibitory Gi-mediated G protein-coupled receptor the downregulated genes (hub genes: IL7r, rt1-bb, rt1-bb1, rt1-da, rt1-ba, cd74, cxcr3, vcam1, ccl5, bin1 neuroinflammation spreads after injury, and neurotransmission through Gi-mediated G protein-coupled receptors Authors Hong Zeng , Li Cheng , De-Zhi Lu , Shuai Fan , Ke-Xin Wang , Li-Li Xu , Bin Cai , Mou-Wang Zhou GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders

  • Session VIII * | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem

    Characterization of Phenotypes Associated with GPR110 Deletion Hee-Yong Kim Abstract "G-protein coupled receptor Synaptamide, an endogenous ligand for GPR110, binds to the N-terminal G-protein autoproteolysis-inducing GPR110 is also highly expressed in the kidney, however, little is known about the function of this receptor

  • CircFKBP5 Suppresses Apoptosis and Inflammation and Promotes Osteogenic Differentiation

    dual-luciferase reporter, RNA immunoprecipitation (RIP), and pull-down assays were used to confirm the binding between miR-708-5p and circFKBP5 or G-protein-coupled receptor (GPCR)-kinase interacting protein 2 ( GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders

  • Ep 156 with Dr. Justin English

    innovating technologies to solve broad questions in pharmacology, with a specific focus on G-protein coupled receptor

  • Ep 44 with Dr. Steven Foord

    identification of RAMPs (solving some CGRP family issues) and the GABA B, carboxylic, and nicotinic acid receptors

  • Applying Pharmacology to Drug Discovery

    hours total Get Started Premium Members benefits: - Subscribe and save 25% on every GPCR Course - Early-bird My interests are in receptor theory, pharmacology applied to drug discovery and allosteric protein function

  • Neurotoxicity and accumulation of CPPD quinone at environmentally relevant concentrations in Caenorhabditis elegans

    Meanwhile, exposure to CPPDQ (0.01-10 μg/L) decreased head thrash, body bend, and forward turn, and increased Additionally, among examined G protein-coupled receptor (GPCR) genes, exposure to CPPDQ (0.01-10 μg/L GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders

  • Ep 112 with Julia Gardner

    Julia studies the mechanisms of 'biased signaling' at GPCRs, with a specific focus on the chemokine receptor

  • Ep 66 with Dr. Antony A. Boucard Jr

    interest in the cardiovascular system by investigating the structure of the Angiotensin and Urotensin receptors through various biochemical approaches centered in the elucidation of ligand binding pocket determinants

  • Ep 146 with Dr Michael Feigin

    Craig Malbon at SUNY Stony Brook studying the role of G-protein coupled receptors (GPCRs) and their regulators discussed his research on cell polarity and its role in cancer progression, his work on G-protein coupled receptors they face in studying GPCRs due to their low expression levels and the difficulty of localizing these receptors He also discussed his work on G-protein coupled receptors (GPCRs) in breast cancer, identifying GPR161 they face in studying GPCRs due to their low expression levels and the difficulty of localizing these receptors

  • Sponsorship Prospectus for Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem

    Workshop 2024, a premier scientific meeting bringing together leaders and innovators in G Protein-Coupled Receptor discussions, workshops, and networking sessions covering the latest advancements and challenges in Membrane Receptor Additional Sponsorship Opportunities: Networking Reception Sponsorship Conference Cup and T-Shirt Sponsorship Up Traveling Tips Find essential tips about Mexico City, including transportation options and local insights

  • GPCR Retreat 2023 | Dr. GPCR Ecosystem

    are pleased to welcome you at Le Château Montebello , the 22nd Annual Great Lakes G Protein-Coupled Receptor University of North Carolina at Chapel Hill, unquestionably one of the pioneers involved in deciphering how receptor Finally, Bienvenue and we hope you will enjoy your stay in Montebello and find the Retreat stimulating

  • Ep 12 with Dr. Antonella Di Pizio

    Today, Antonella has expanded her research to olfactory GPCRs and trace amine receptors.

  • Ep 22 with Dr. Kari Johnson

    career, the recurring theme in Kari’s work has been GPCRs and more specifically Metabotropic Glutamate Receptors

  • Ep 10 with Dr. John Streicher

    John and his team focus on understanding how signal transduction cascades downstream of the opioid receptors

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