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298 items found for "α(2A)-adrenergic receptor"
- Ep 52 with Dr. Benjamin Myers
His group studies the unusual signaling mechanisms employed by these atypical 7-transmembrane receptors
- Ep 157 with Dr. Nagarajan Vaidehi
constrained molecular dynamics simulation methods with emphasis on application to G-protein coupled receptors
- Removing the GPCR-mediated brake on exocytosis enhances insulin action, promotes adipocyte browning, and protects against diet-induced obesity
Current areas of interest include Protease Activated Receptor signaling in the cardiovascular system and regulation of vesicular exocytosis mediated by Gi/o-coupled receptors by G subunit binding to SNAREs
- Cannabinoid compounds to augment L-DOPA treatment in Parkinson's Disease
the Vesicular Monoamine Transporter 2 (VMAT2), Tyrosine Hydroxylase (TH) and Trace Amine Associate Receptor
- G Proteins and GPCRs in Cancer: Novel Precision Targeted and Immunotherapies
His research team has pioneered the study of G proteins and G protein coupled receptors (GPCRs) in human
- Developing a PROTAC to Degrade the Constitutively Active Onco-GPCR in Uveal Melanoma
laboratory at Rockefeller University, where she studies the signaling and degradation of G protein-coupled receptors
- Posters | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Brain Angiogenesis Inhibitor (BAI) proteins are members of group VII of the adhesion G protein-coupled receptor Kordon Abstract "Adhesion G Protein-Coupled Receptors (aGPCRs) are key cell-adhesion molecules involved Ligand binding and mechanical force applied on the ECR regulate receptor function. alterations during neurodevelopment Mariam Melkumyan Abstract "GPR110, an adhesion G protein coupled receptor will give insight on the mechanism underlying the behavioral consequences associated with the GPR110 receptor
- Ep 80 with Dr. Andrew Tobin
consecutive Wellcome Trust Senior Research Fellowships Andrew established a reputation in the field of receptor
- Ep 61 with About Dr. Marta Filizola
function of important classes of membrane proteins and prominent drug targets, including G protein-coupled receptors
- Ep 17 with Dr. Yamina Berchiche
During the past 2 decades, my research mainly focused on chemokine receptor structure/function relationships
- Ep 85 with Nicholas Holliday
Nottingham in 2006, where he is now Associate Professor, establishing a lab focused on G protein-coupled receptor
- Ep 63 with Dr. Khaled Abdelrahman
Neuroscience at the University of Ottawa as a Postdoctoral Fellow to explore novel G protein-coupled receptor
- Ep 74 with Dr. Daniel Wacker
Ray Stevens in 2013 solving several GPCR crystal structures, including that of the first serotonin receptor
- Natural carboxyterminal truncation of human CXCL10 attenuates glycosaminoglycan binding, CXCR3A signaling and lymphocyte chemotaxis, while retaining angiostatic activity
chemotaxis of activated T cells and natural killer (NK) cells via interaction with its G protein-coupled receptor (GPCR), CXC chemokine receptor 3 (CXCR3).
- Short-chain fatty acids and cancer
function as energy sources through β-oxidation and regulate macromolecular synthesis, G protein-coupled receptor
- Ep 147 with Dr. Demet Araç
backgrounds, and career paths, with a focus on their experiences in the field of GPCR (G protein-coupled receptor Scientists Demet and Yamina discussed the progress of their research in the GPCR (G protein-coupled receptor They also discussed the importance of the extracellular region of these receptors and its potential as
- Ep 141 with Dr Tobi Langenhan
of Dr Andreas Russ at the Department of Biochemistry and first came across GPCRs, particularly the receptor
- Ep 56 with Dr. Adriano Marchese
his postdoctoral training in Jeff Benovic’s laboratory studying the regulation of G protein-coupled receptor
- Retreat | Dr. GPCR Ecosystem
membership will grant you access to a wealth of resources, research, and discussions on your favorite receptor
- Itaconate in host inflammation and defense
modification, and gene expression and to signal extracellularly through binding the G protein-coupled receptor
- Ep 109 with Dr. Katarina Nemec
Ljubljana, Slovenia, and at the University of Bonn, Germany, working initially on the role of prostaglandin receptor
- Ep 89 with Dr. Patrick Sexton
, a corresponding member of the International Union of Basic and Clinical Pharmacology Committee on Receptor
- GPR37 promotes colorectal cancer against ferroptosis by reprogramming lipid metabolism via p38-SCD1 axis
This study demonstrates that GPR37, a GPCR receptor, is highly expressed in CRC.
- A journey from Duke to McGill along the dopamine circuit
Laboratory directed by Jean-Charles Schwartz in Paris, where he cloned and characterized dopamine D2 and D3 receptor
- Unbiased multitissue transcriptomic analysis reveals complex neuroendocrine regulatory networks mediated by spinal cord injury-induced immunodeficiency
Zfhx2, Gpr83, and Chrm2) were enriched in pathways related to inhibitory Gi-mediated G protein-coupled receptor neuroinflammation spreads after injury, and neurotransmission through Gi-mediated G protein-coupled receptors
- Targeting adenosine signaling for immuno-oncology
Friday, November 3rd / 4:35 PM Abstract "Adenosine (ADO) signaling through A2A and A2B G protein-coupled receptors
- Efferocytes release extracellular vesicles to resolve inflammation and tissue injury via prosaposin-GPR37 signaling
EVs express prosaposin, which binds to macrophage GPR37 to increase expression of the efferocytosis receptor
- High Metabolite Concentrations in Portal Venous Blood as a Possible Mechanism for Microbiota Effects on the Immune System, and Western Diseases
Deficiency of SCFA would lead to pro-inflammatory immune cell skewing through insufficient G-protein coupled receptor