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276 items found for "Cell cycle"
- Fly casting with ligand sliding and orientational selection supporting complex formation of a GPCR..
ligand-receptor binding by searching large-scale motions accompanied with stable maintenance of the fragile cell-membrane
- Biased GPCR signaling by the native parathyroid hormone-related protein 1 to 141 relative to its...
Here, we demonstrate using various fluorescence imaging approaches at the single cell level to measure
- Regulator of G Protein Signaling 20 Correlates with Long Intergenic Non-Coding RNA (lincRNAs)...
associated with various cancers, with some members of the RGS family being associated with liver cancer as well < 0.001), RGS20 was found to be an important factor for survival in four other cancers (clear renal cell
- 📰 GPCR Weekly News, February 19 to 25, 2024
GPR3 After wounding, a G-protein coupled receptor promotes the restoration of tension in epithelial cells glutamatergic neurons GPCRs in Oncology and Immunology TIPE proteins control directed migration of human T cells
- An overview of the compartmentalized GPCR Signaling: Relevance and Implications
positioning of the cannabinoid CB1 receptor on the outer mitochondrial membrane of skeletal and myocardial cells kinetics of signaling and the spatial organization of signaling effectors, including G proteins, adenylyl cyclases Sustained cyclic AMP production by parathyroid hormone receptor endocytosis. GPCRomics: GPCR Expression in Cancer Cells and Tumors Identifies New, Potential Biomarkers and Therapeutic
- Endothelin-1 Stimulates PAI-1 Protein Expression via Dual Transactivation Pathway Dependent ROCK...
to the carboxy region, Smad2 transcription factor can be phosphorylated in the linker region as<br />well Smad2L and protein expression of PAI-1 induced by endothelin-1 (ET-1) in bovine aortic endothelial cells
- New role of β-arrestins in MOR signaling
compartments and their activation is generally related to inhibiting neurotransmission by hyperpolarizing the cell signaling, Shiraki et al., explored the function of β-arrestin 2 in MOR signaling using the SH-SY5Y cell
- Ode to GPCRs
, which produces the archetypical secondary messenger cyclic AMP (cAMP), plays in cellular signaling. Rodbell for their discovery of G-proteins and the role of these proteins in signal transduction in cells .[40–46] In his work, Rodbell demonstrated that signal transduction through the cell membrane involves transduction that requires GTP is G-protein and was the first to isolate it through his work on leukemia cells Non-traditional roles of G protein-coupled receptors in basic cell biology.
- The sixth transmembrane region of a pheromone G-protein coupled receptor, Map3, is implicated in ...
In ascomycete fungi including yeasts, mating between cells of opposite mating type depends on the molecular
- Exploring the Breakthroughs in GPCR Research
interactions of the serotonin1A receptor Industry News Neurocrine Biosciences Announces Conference Call in Korea GPCR Events, Meetings, and Webinars September 18, 2024 | FREE Webinar - The value of GPCR cell-based
- 📰 GPCR Weekly News, March 6 to 12, 2023
Oncology and Immunology GPR176 Promotes Cancer Progression by Interacting with G Protein GNAS to Restrain Cell ) Sosei Heptares Receives Approval for Change of Market Listing Segment to the Tokyo Stock Exchange Call
- A role for BET proteins in regulating basal, dopamine-induced and cAMP/PKA-dependent ...
it binds more readily to acetylated histones at promoters and enhancers; moreover, in non-neuronal cells
- 📰 GPCR Weekly News, June 10 to 16, 2024
Scientist Senior Research Associate/Associate Scientist, Protein Science Post-Doctoral Fellow—Pharmacology/Cell
- 📰 GPCR Weekly News, March 13 to 19, 2023
opportunity to generate proprietary chemo-informatics for GPCR drug discovery - Design Pharmaceuticals Call NEW Training School on “Cell-based assays to study Adhesion GPCR function".
- 📰 GPCR Weekly News, February 20 to 26, 2023
Reviews, GPCRs, and more Cell-trafficking impairment in disease-associated LPA6 missense mutants and understanding of the role of muscarinic receptors in the molecular pathology and treatment of schizophrenia Call
- 📰 GPCR Weekly News, July 10 to 16, 2023
GPCRs in Neuroscience The head mesodermal cell couples FMRFamide neuropeptide signaling with rhythmic
- Self-docking and cross-docking simulations of G protein-coupled receptor-ligand complexes
ligand type and receptor activation state G protein-coupled receptors (GPCR) are the largest family of cell
- 📰 GPCR Weekly News, May 15 to 21, 2023
FREE Symposium - IPI Surfacing (June 15, 2023) Training School on “Cell-based assays to study Adhesion
- 📰 GPCR Weekly News, August 7 to 13, 2023
autism spectrum disorders GPCRs in Oncology and Immunology Molecular characterization of breast cancer cell
- 📰 GPCR Weekly News, April 8 to 14, 2024
acetylcholine receptor-mediated calcium responses and the recruitment of β-arrestin in HSY human parotid cells and Pharmacology Addex Therapeutics to Release Full-Year 2023 Financial Results and Host Conference Call
- Exendin-4 Attenuates Remodeling in the Remote Myocardium of Rats After an Acute Myocardial ...
of collagen I/III with higher levels of reactive oxygen species (ROS) and inflammatory cytokines, as well They also showed higher protein levels of phospho-glycogen synthase kinase-3β (p-GSK3β), as well as total , phosphorylated, and nuclear β-catenin with a concomitant decrease in the levels of cyclic adenosine Mechanisms are assumed to occur in the cardiomyocytes and/or other resident cells such as fibroblast.
- 📰 GPCR Weekly News, January 29 to February 4, 2024
the Classified GPCR News from January 29th to February 4th, 2024 Adhesion GPCRs CELSR1, a core planar cell and FZD7 Loss-of-function of GNAL dystonia gene impairs striatal dopamine receptors-mediated adenylyl cyclase / cyclic AMP signaling pathway The non-nutritive sweetener sucralose increases β-arrestin signaling at prediction Structural and Molecular Insights into GPCR Function Structural insights into membrane adenylyl cyclases
- 📰 GPCR Weekly News, April 1 to 7, 2024
convolutional network GPCRs in Cardiology, Endocrinology, and Taste Dissecting a Brake for Airway Smooth Muscle Cell
- Decoding β-Arrestins: from Structure to function
activate specific G protein families, others are more versatile, yielding diverse responses based on cell-specific This includes proteins like AP-2 and clathrin, vital for internalization, as well as MAPK cascade kinases signaling pathways governed by β-arrestins, which exhibit increased or reduced activity within distinct cell
- GPCR Updates: Celebrating Breakthroughs, New Course Launches Soon, and Exclusive Discounts! | Aug 26 - Sep 1, 2024
Adiso Announces Groundbreaking Research Highlighting ADS024 a Novel Oral Agent for Neuroinflammation Call , 2024 | 4th Transatlantic ECI GPCR Symposium September 18, 2024 | FREE Webinar - The value of GPCR cell-based
- 📰 GPCR Weekly News, November 6 to November 12, 2023
hedgehog pathway repression in tissue morphogenesis TIPE proteins control directed migration of human T cells
- 📰 GPCR Weekly News, March 11 to 17, 2024
The Prostaglandin E2 EP3 Receptor Has Disparate Effects on Islet Insulin Secretion and Content in β-cells
- 📰 GPCR Weekly News, January 1 to 7, 2024
mechanism of antihistamines recognition and regulation of the histamine H1 receptor [Enhancement of mast cells