The choice of model systems, such as yeast, bacteria, or mammalian cells, can heavily influence the method's application of DMS to a wider array of biological systems, including multicellular organisms and human cells

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wide array of physiological and disease functions, yet knowledge of their role in colon cancer stem cell A truncated form of β-catenin, ∆N133β-catenin, devoid of lysine, as well as serine/threonine residues

classical G-protein-coupled receptor (GPCR), whereas C5aR2 is a nonclassical GPCR that tailors immune cell

Kv7 channels via Gi/o protein signalling and modulates excitability of human induced pluripotent stem cell-derived Updates in GPCR Research Alared: Solvatochromic and Fluorogenic Red Amino Acid for Ratiometric Live-cell

recombinant protein standards for quantitative Western blot analysis of cannabinoid CB1 receptor density in cell

depression was involved in the biological process of GPCR signal transduction, hormone metabolism and nerve cell

discuss the physiological significance of GPCR scramblase activity and the modes of its regulation in cells

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Comparative interactome analysis of α-arrestin families in human and Drosophila Functional diversification of cell of Gi-coupling receptors via engineered Gt and Nb35 application Imaging GPCR Dimerization in Living Cells

GPCRs in Oncology and Immunology A2aR on lung adenocarcinoma cells: A novel target for cancer therapy 15, 2023) GPCRs in drug discovery: challenges & solutions (June 19 - 23, 2023) Training School on “Cell-based

evolution of GPCRs, and expand our knowledge of the cladoceran GPCR gene repertories which in part, mediate cell

ligand-receptor binding by searching large-scale motions accompanied with stable maintenance of the fragile cell-membrane

Here, we demonstrate using various fluorescence imaging approaches at the single cell level to measure

associated with various cancers, with some members of the RGS family being associated with liver cancer as well < 0.001), RGS20 was found to be an important factor for survival in four other cancers (clear renal cell

GPR3 After wounding, a G-protein coupled receptor promotes the restoration of tension in epithelial cells glutamatergic neurons GPCRs in Oncology and Immunology TIPE proteins control directed migration of human T cells

to the carboxy region, Smad2 transcription factor can be phosphorylated in the linker region as<br />well Smad2L and protein expression of PAI-1 induced by endothelin-1 (ET-1) in bovine aortic endothelial cells

compartments and their activation is generally related to inhibiting neurotransmission by hyperpolarizing the cell signaling, Shiraki et al., explored the function of β-arrestin 2 in MOR signaling using the SH-SY5Y cell

August 2022 "A confluence of factors has renewed interest in the scientific understanding and translational

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In ascomycete fungi including yeasts, mating between cells of opposite mating type depends on the molecular

it binds more readily to acetylated histones at promoters and enhancers; moreover, in non-neuronal cells

Scientist Senior Research Associate/Associate Scientist, Protein Science Post-Doctoral Fellow—Pharmacology/Cell

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Reviews, GPCRs, and more Cell-trafficking impairment in disease-associated LPA6 missense mutants and understanding of the role of muscarinic receptors in the molecular pathology and treatment of schizophrenia Call

GPCRs in Neuroscience The head mesodermal cell couples FMRFamide neuropeptide signaling with rhythmic

ligand type and receptor activation state G protein-coupled receptors (GPCR) are the largest family of cell

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