Fung has spent significant time in the industry studying membrane proteins, antibodies, and HTS methods

in his independent laboratory is focused on developing new pharmacological tools via chemistry and protein

can overcome these obstacles by producing high-quality antibodies that more accurately mimic natural protein

Senior Principal Research Fellow and Director, ARC Centre for Cryo-electron Microscopy of Membrane Proteins

Aaron is currently the Chief Scientific Officer and VP of Protein Engineering. Aaron has a proven track record as a biologics leader as he led teams to discover and develop novel first-in-class

His lab has worked on building large-scale ways of empirically exploring questions in protein biochemistry

elevated in disease settings, where the largest group of CC-chemokines are the macrophage inflammatory proteins

I was fascinated by the multitude of processes that are regulated/dysregulated by GPCRs and RGS proteins A fungal serine protease allergen with GPCR-modulating features was discovered as a new biomarker and

My interests are in receptor theory, pharmacology applied to drug discovery and allosteric protein function

characterized by a unique expression profile of ion channels, GPCR signaling molecules, synaptic vesicle cycle proteins

The adapter protein 3BP2 is mutated in Cherubism.

GSEA demonstrated that neutrophil degranulation, signaling by Interleukins, GPCR-ligand binding, G alpha

My interests are in receptor theory, pharmacology applied to drug discovery and allosteric protein function

My interests are in receptor theory, pharmacology applied to drug discovery and allosteric protein function

Further investigations in vitro and in vivo revealed that the levels of an anti-apoptotic protein, Bcl

underlying this synergistic pharmacodynamic interaction, liquid chromatography-mass spectrometry-based proteomic capture pancreatic cancer cell responses to gemcitabine and trabectedin, alone and combined, at the proteome Part I described the proteomic workflow and drug effects on the upstream portion of the SPD model related Drug combination effects on protein changes in the cell cycle- and apoptosis pathways contribute to the multi-scale quantification platform for evaluating drug effects across multiple scales, spanning the proteomic

Neitzel , Jessica Cornell , Samantha Rea , Ian Mills , Maya S Silver , Jovanni D Ahmad , Konstantin G

My expertise includes biochemical approaches, proteomics and transcriptomics to name a few. My main topics were protein biochemistry, Drosophila husbandry, and genetics.

< GPCR News < GPCRs in Oncology and Immunology Increased protease-activated receptor 1 autoantibodies

< GPCR News < GPCRs in Oncology and Immunology Metallo-protease Peptidase M84 from Bacillusaltitudinis Abstract "We have purified Peptidase M84 from Bacillus altitudinis in an effort to isolate anticancer proteases This metallo-protease had no discernible impact on normal cell survival, but it specifically induced

They also shared their preference for small molecule therapies over protein therapeutics.

< GPCR News < GPCRs in Oncology and Immunology S1P Signaling Genes as Prominent Drivers of BCR-ABL1-Independent