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362 items found for "Vivian G Oehler"
- GPR110, a receptor for synaptamide, expressed in osteoclasts negatively regulates osteoclastogenesis
Although some G-protein coupled receptors (GPCRs) were reported to play roles in osteoblast function,
- TAS2R supports odontoblastic differentiation of human dental pulp stem cells in the inflammatory...
The G protein and intracellular Ca2+ were detected, respectively, by qPCR and Fluo-4AM Ca2+ fluorescent
- 📰 GPCR Weekly News
GPCRs in Oncology and Immunology Pan-cancer functional analysis of somatic mutations in G protein-coupled Deadline February 12, 2023 Current Technologies To Understand G-Protein-Coupled Receptor Molecular Pharmacology
- Orion Announces The Rapid Lead Optimization Of Ob-004 - A Ccr2 Antagonist
30, 2021 -- Orion Biotechnology , a clinical stage company unlocking the therapeutic potential of G
- Domain Therapeutics and Explicyte enter partnership agreement in immuno-oncology
, a biopharmaceutical company specializing in the discovery and development of new drugs targeting G
- Isoform-and ligand-specific modulation of adhesion GPCR ADGRL3/Latrophilin3 by a synthetic binder
September 2022 "Adhesion G protein-coupled receptors (aGPCRs) are cell-surface proteins with large extracellular
- Finding needles in haystacks: Omass unveils pipeline aimed at tough-to-drug targets
The targets, including G protein-coupled receptors (GPCRs), intracellular protein complexes and solute
- Label-free LC-MS based assay to characterize small molecule compound binding to cells
In one example, to study a G protein coupled receptor (GPCR), we used one antagonist as probe and multiple
- Endogenous ligand recognition and structural transition of a human PTH receptor
PTH-related peptide (PTHrP) bind to the parathyroid hormone receptor 1 (PTH1R) and activate the stimulatory G-protein
- Discovery and In Vivo Evaluation of ACT-660602: A Potent and Selective Antagonist of the Chemokine..
Chemokine Receptor CXCR3 for Autoimmune Diseases "The chemokine receptor CXCR3 is a seven-transmembrane G-protein-coupled
- Targeting CXCR1 and CXCR2 receptors in cardiovascular diseases
Numerous intracellular mediators are activated by these G protein-coupled receptors based on several
- VIB spin-off Confo Therapeutics Enters Collaborative Agreement with Regeneron
platform, which uses conformationally selective VHH antibodies – ConfoBodies® – to stabilize GPCRs (G
- Targeting CXCR1 and CXCR2 receptors in cardiovascular diseases
Numerous intracellular mediators are activated by these G protein-coupled receptors based on several
- GPCR kinases generate an APH1A phosphorylation barcode to regulate amyloid-β generation
August 2022 "Emerging evidence suggests that G protein-coupled receptor (GPCR) kinases (GRKs) are associated
- Multifunctional role of GPCR signaling in epithelial tube formation
Rho1 signaling is activated by G-protein-coupled receptor (GPCR) signaling at the cell surface.
- Orion Shares New Data on its Latest Best-in-Class Drug Candidate
Biotechnology Canada Ltd, a drug discovery and development company unlocking the therapeutic potential of G
- Molecular mechanism of allosteric modulation for the cannabinoid receptor CB1
September 2022 "Given the promising clinical value of allosteric modulators of G protein-coupled-receptors
- Cholesterol occupies the lipid translocation pathway to block phospholipid scrambling by a GPCR
September 2022 "Class A (rhodopsin-like) G protein-coupled receptors (GPCRs) are constitutive phospholipid
- Endogenous ligand recognition and structural transition of a human PTH receptor
PTH-related peptide (PTHrP) bind to the parathyroid hormone receptor 1 (PTH1R) and activate the stimulatory G-protein
- Multifunctional role of GPCR signaling in epithelial tube formation
Rho1 signaling is activated by G-protein-coupled receptor (GPCR) signaling at the cell surface.
- 📰 GPCR Weekly News, April 1 to 7, 2024
through the μ opioid receptor GPCR Binders, Drugs, and more Predicting associations between drugs and G and Exhibition June 2 - 7, 2024 | Chemotactic Cytokines June 9 - 14, 2024 | 2024 Phosphorylation and G-Protein
- Opioid Receptors and Protonation-Coupled Binding of Opioid Drugs
Opioid receptors are G-protein-coupled receptors (GPCRs) part of cell signaling paths of direct interest
- Membrane Lipids Are an Integral Part of Transmembrane Allosteric Sites in GPCRs: A Case Study of...
Cannabinoid CB1 Receptor Bound to a Negative Allosteric Modulator, ORG27569, and Analogs "A growing number of G-protein-coupled
- The Gluopsins: Opsins without the Retinal Binding Lysine
They are G-protein-coupled receptors and bind as ligand retinal, which is bound covalently to a lysine
- Fluorescent Ligands Targeting Intracellular Allosteric Binding Site of the Chemokine Receptor CCR2
August 2022 "Fluorescently labeled ligands are versatile molecular tools to study G protein-coupled receptors
- Tracking receptor motions at the plasma membrane reveals distinct effects of ligands on CCR5...
August 2022 "G-protein-coupled receptors (GPCR) are present at the cell surface in different conformational
- Dopamine D 1 receptor-mediated β-arrestin signaling: Insight from pharmacology, biology, behavior...
A major pan-receptor focus has been to identify GPCR-selective ligands that have bias in G protein-dependent
- 📰 GPCR Weekly News, March 4 to 10, 2024
/o protein responses of some native GPCRs in neurons Beyond the Nucleus: Plastic Chemicals Activate G and Exhibition June 2 - 7, 2024 | Chemotactic Cytokines June 9 - 14, 2024 | 2024 Phosphorylation and G-Protein