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Cdc42 axis Published date June 26, 2023 Abstract "The functional association between stimulation of G-protein

, Titli Nargis , Kierstin Webster , Sarah A Tersey , Ryan M Anderson , Raghavendra G Mirmira Tags G-protein

the tumor microenvironment (TME), purinergic receptors such as ATP-gated ion channels P2X1-5 and G protein-coupled

G-protein-coupled receptors (GPCRs) are the most intensively studied drug targets but are underexplored

US28 is a virally encoded G protein-coupled receptor (GPCR) that is essential for silent infections within to establish a quiescent infection, resulting in a fully productive lytic infection able to produce progeny

sterile and infectious inflammation Published date January 1, 2023 Abstract We recently found that the G protein

Long-COVID is currently under heavy scrutiny and existing data on the role of auto-immune reaction to G-protein

Additionally, among examined G protein-coupled receptor (GPCR) genes, exposure to CPPDQ (0.01-10 μg/L

NPFF regulates a variety of physiological functions by binding to a G protein-coupled receptor (GPCR)

Transforming growth factor-β (TGFβ) is essential for alveologenesis and lung repair, and the G protein Cyclical mechanical stretch-induced TGFβ activation required Gαq/11 signalling and serine protease activity

for AGPCR24 Attendees About Jin-Peng Sun "Since starting my laboratory in 2011, I has focused on G protein For arrestin mediated biased signaling, we have proposed the “flute model” and “poly proline region docking

My interests are in receptor theory, pharmacology applied to drug discovery and allosteric protein function

mission is to discover and develop highly effective cancer therapeutics by targeting heteromers of G protein-coupled

salmoides) Published date October 24, 2024 Abstract "CC chemokine receptors (CCRs), the numbers of the G protein-coupled

This autoimmune loop in psoriasis pathogenesis is influenced by G protein-coupled receptor (GPCR) signalling

GPR15 is a G protein-coupled receptor (GPCR) located on chromosome 3 and has similarity in its sequence

Further investigations in vitro and in vivo revealed that the levels of an anti-apoptotic protein, Bcl

underlying this synergistic pharmacodynamic interaction, liquid chromatography-mass spectrometry-based proteomic capture pancreatic cancer cell responses to gemcitabine and trabectedin, alone and combined, at the proteome Part I described the proteomic workflow and drug effects on the upstream portion of the SPD model related Drug combination effects on protein changes in the cell cycle- and apoptosis pathways contribute to the multi-scale quantification platform for evaluating drug effects across multiple scales, spanning the proteomic

Previously, we identified potent positive crosstalk between insulin/IGF-1 receptors and G protein-coupled

Regulator of G protein signaling 20 (RGS20) is identified as an upregulated factor in many cancers, yet

GPR37 is an orphan G protein-coupled receptor (GPCR) that is implicated in different physiological pathways

analysis revealed seven significantly enriched biological processes affected by PR and associated with G protein-coupled

Adhesion GPCR Workshop 2024, a premier scientific meeting bringing together leaders and innovators in G Protein-Coupled Complimentary exhibition booth in a prominent location at the event venue. Gold Sponsor Prominent recognition as a Gold sponsor in all promotional materials.

My expertise includes biochemical approaches, proteomics and transcriptomics to name a few. My main topics were protein biochemistry, Drosophila husbandry, and genetics.

Abstract " Aims: A causal link between non-ischaemic heart failure (HF) and humoral autoimmunity against G-protein-coupled

received my degree in biochemistry from Leipzig University (Germany) being already fascinated by G protein-coupled

GPCR, an ecosystem designed to bring together stakeholders interested in using G-Protein Coupled Receptors San Francisco under the guidance of Professor Shaun Coughlin where she worked on the newly discovered protease-activated program is to gain a thorough and mechanistic understanding of processes that control cell signaling by protease-activated Her laboratory is the recognized expert on protease-activated receptors, particularly PAR1, and over

They also shared their preference for small molecule therapies over protein therapeutics.