Search Results
329 items found for "receptor binding"
- Ep 117 with Dr. Pierre Eftekhari
The majority of my research is concentrated on rhodopsin family with a few works on metabotropic receptor
- Ep 41 with Dr. Terry Kenakin
His interests are in receptor pharmacology, allosteric protein function, and drug discovery. Dr.
- Ep 40 with Dr. Brian Bender
where he used structural models of GPCRs to virtually screen large compound libraries with the goal of finding new chemical matter to probe understudied and orphan receptors.
- Ep 108 with Dr. Kenneth A. Jacobson
adapts interdisciplinary approaches (synthesis, modeling, pharmacology) to study G protein-coupled receptors
- Ep 52 with Dr. Benjamin Myers
His group studies the unusual signaling mechanisms employed by these atypical 7-transmembrane receptors
- Cannabinoid compounds to augment L-DOPA treatment in Parkinson's Disease
the Vesicular Monoamine Transporter 2 (VMAT2), Tyrosine Hydroxylase (TH) and Trace Amine Associate Receptor
- Ep 79 with Dr. Graeme Milligan
His main research group centers on the function, structure, and regulation of G protein-coupled receptors
- Ep 67 with Dr. Graham Ladds
In 2020, he was promoted to a Readership/Professor in Receptor Pharmacology and was elected a Fellow
- G Proteins and GPCRs in Cancer: Novel Precision Targeted and Immunotherapies
His research team has pioneered the study of G proteins and G protein coupled receptors (GPCRs) in human
- Ep 115 with Dr. Paul J. Gasser
is currently focused on understanding the signal transduction pathways activated by beta-adrenergic receptors
- Ep 157 with Dr. Nagarajan Vaidehi
constrained molecular dynamics simulation methods with emphasis on application to G-protein coupled receptors
- Developing a PROTAC to Degrade the Constitutively Active Onco-GPCR in Uveal Melanoma
laboratory at Rockefeller University, where she studies the signaling and degradation of G protein-coupled receptors
- Ep 14 with Dr. Bryan Roth
Bryan got fascinated with receptors after attending the lecture of a visiting professor on neurotransmission
- Principles of Pharmacology in Drug Discovery II
Receptor data shows how GPCR control of cellular function goes far beyond simple second messenger production Early-bird registration is over.
- GPR37 promotes colorectal cancer against ferroptosis by reprogramming lipid metabolism via p38-SCD1 axis
This study demonstrates that GPR37, a GPCR receptor, is highly expressed in CRC. GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders
- Functional Assessment of Cancer-Linked Mutations in Sensitive Regions of Regulators of G Protein Signaling Predicted by Three-Dimensional Missense Tolerance Ratio Analysis
January 1, 2023 Abstract Regulators of G protein signaling (RGS) proteins modulate G protein-coupled receptor complimentary cellular and biochemical approaches, proteins were tested for effects on GPCR-G α activation, G α binding These findings show that 3DMTR identified intolerant residues that overlap with cancer-linked mutations GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders
- PAXIP1-AS1 is associated with immune infiltration and predicts poor prognosis in ovarian cancer
GSEA demonstrated that neutrophil degranulation, signaling by Interleukins, GPCR-ligand binding, G alpha I signaling events, VEGFAVEGFR-2 signaling pathway, naba secreted factors, Class A 1 Rhodopsin-Like Receptors GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders
- Ep 147 with Dr. Demet Araç
backgrounds, and career paths, with a focus on their experiences in the field of GPCR (G protein-coupled receptor Scientists Demet and Yamina discussed the progress of their research in the GPCR (G protein-coupled receptor They also discussed the importance of the extracellular region of these receptors and its potential as Both agreed that one should find work exciting and interesting, as life is too short to spend doing things
- Ep 63 with Dr. Khaled Abdelrahman
Neuroscience at the University of Ottawa as a Postdoctoral Fellow to explore novel G protein-coupled receptor
- Ep 17 with Dr. Yamina Berchiche
During the past 2 decades, my research mainly focused on chemokine receptor structure/function relationships
- Ep 85 with Nicholas Holliday
Nottingham in 2006, where he is now Associate Professor, establishing a lab focused on G protein-coupled receptor
- Ep 80 with Dr. Andrew Tobin
consecutive Wellcome Trust Senior Research Fellowships Andrew established a reputation in the field of receptor The vehicle by which Andrew is translating fundamental findings to commercial products is Keltic Pharma
- Ep 61 with About Dr. Marta Filizola
function of important classes of membrane proteins and prominent drug targets, including G protein-coupled receptors
- Ep 74 with Dr. Daniel Wacker
Ray Stevens in 2013 solving several GPCR crystal structures, including that of the first serotonin receptor
- The pyruvate-GPR31 axis promotes transepithelial dendrite formation in human intestinal dendritic cells
G-protein-coupled receptors (GPCRs) sense metabolites and can act as key mediators that translate gut GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders
- Investigating isoform switching in RHBDF2 and its role in neoplastic growth in breast cancer
Therefore, there is always an immense need to find promising and novel anti-cancer drug targets. were more observant, specifically MAPK signalling pathways, GPCR signalling pathways, and toll-like receptor Authors Mehar Masood, Madahiah Bint E Masood, Noor Us Subah, Maria Shabbir, Rehan Zafar Paracha, Mehak GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders
- High Metabolite Concentrations in Portal Venous Blood as a Possible Mechanism for Microbiota Effects on the Immune System, and Western Diseases
Deficiency of SCFA would lead to pro-inflammatory immune cell skewing through insufficient G-protein coupled receptor GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders
- GPR176 Promotes Cancer Progression by Interacting with G Protein GNAS to Restrain Cell Mitophagy in Colorectal Cancer
Colorectal Cancer Published date March 11, 2023 Abstract " GPR176 belongs to the G protein-coupled receptor GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders