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59 items found for " Amanda T Goodwin"

Posts (40)

  • Induced Human Regulatory T Cells Express the Glucagon-like Peptide-1 Receptor

    Recent studies in experimental animals have shown that certain subsets of T cells express functional In contrast, less is known about the expression and function of the GLP-1R in human T cells. Here, we provide evidence that activated human T cells express GLP-1R. Analysis of CD4+ T cells activated under T helper (Th) 1, Th2, Th17 and regulatory T (Treg) cell differentiation GLP-1R in human CD4+ T cells.

  • GPR15 expressed in T lymphocytes from RA patients is involved in leukocyte chemotaxis to the...

    October 2022 GPR15 expressed in T lymphocytes from RA patients is involved in leukocyte chemotaxis to of synovial fluid and peripheral blood were analyzed for CD45+CD3+CD4+GPR15+ and CD45+CD3+CD8+GPR15+ T Statistical analysis included Kruskal-Wallis test, T-test, or Mann-Whitney U test, according to data The frequencies of CD4+/CD8+ GPR15+ T lymphocytes are higher in RA patients comparing with healthy subjects Also, the frequency CD4+/CD8+ GPR15+ T lymphocytes are higher in synovial fluid of established RA patients

  • Divergent roles for the gut intraepithelial lymphocyte GLP-1R in control of metabolism, microbiota..

    Divergent roles for the gut intraepithelial lymphocyte GLP-1R in control of metabolism, microbiota, and T anti-inflammatory actions of GLP-1RAs require the gut IEL GLP-1R to selectively restrain local and systemic T effects are mediated by the suppression of gut IEL effector functions linked to the dampening of proximal T

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Other Pages (19)

  • The combination of brentuximab vedotin and chidamide synergistically suppresses the proliferation of T-cell lymphoma cells through the enhancement of apoptosis

    The combination of brentuximab vedotin and chidamide synergistically suppresses the proliferation of T-cell through the enhancement of apoptosis Published date November 3, 2023 Abstract " Purpose: Peripheral T-cell HH cells, originating from an aggressive cutaneous T-cell lymphoma, were used as an experimental model Conclusion: The use of chidamide in conjunction with BV may positively affect and enhance T-cellular Junpei Soeda , Yoshihide Kakimoto Tags Apoptosis , Bcl-2 , Brentuximab vedotin , CDC45 , Chidamide , T-cell

  • The EBI2 receptor is coexpressed with CCR5 in CD4+ T cells and boosts HIV-1 R5 replication

    < GPCR News < GPCRs in Oncology and Immunology The EBI2 receptor is coexpressed with CCR5 in CD4+ T cells Methods: We identified GPCRs expressed in primary CD4+CCR5+ T cells by multi-RT-qPCR. Results: We showed that EBI2 is naturally expressed in primary CD4+CCR5+ T cells, and that CCR5 and EBI2 in blood and lymphoid tissues, the constant EBI2 activation might increase HIV replication in CD4+ T

  • Respiratory infections predominate after day 100 following B-cell maturation antigen-directed CAR T-cell therapy

    Immunology Respiratory infections predominate after day 100 following B-cell maturation antigen-directed CAR T-cell important complication after B-cell maturation antigen (BCMA)-directed chimeric antigen receptor (CAR) T-cell We evaluated infections in 99 adults who received a first BCMA-directed CAR T-cell therapy (commercial and investigational autologous BCMA CAR T-cell products at the recommended phase 2 dose) for relapsed Respiratory infections predominate after BCMA CAR T-cell therapy, particularly after day 100.

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