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504 items found for " Chronic obstructive pulmonary disease (COPD)"
Posts (226)
- Regulation of pulmonary surfactant by the adhesion GPCR GPR116/ADGRF5 requires a tethered agonist...
October 2022 Regulation of pulmonary surfactant by the adhesion GPCR GPR116/ADGRF5 requires a tethered A knock-in mouse expressing a non-cleavable GPR116 mutant phenocopies the pulmonary phenotype of GPR116
- GRK2 in cardiovascular disease and its potential as a therapeutic target
August 2022 "Cardiovascular diseases (CVDs) represent the leading cause of death globally.
- Targeting the M1 muscarinic receptor in neurodegenerative disease
April 2022 "By Sophie Bradley | Apr 12, 2022 Summary Sophie Bradley, Translational Sciences Associate Director at Sosei Heptares, recently presented at the Keystone Symposia GPCR Conference, a summary of work performed both at Sosei Heptares and Glasgow University characterizing the role of the muscarinic M1 receptor in cognitive and neurodegenerative disorders and the potential therapeutic benefit of muscarinic M1 selective ligands." Read more at the source #DrGPCR #GPCR #IndustryNews
Other Pages (278)
- Expanding role of CXCR2 and therapeutic potential of CXCR2 antagonists in inflammatory diseases and cancers
and Immunology Expanding role of CXCR2 and therapeutic potential of CXCR2 antagonists in inflammatory diseases receptor (GPCR) and plays important roles in various inflammatory diseases and cancers, including chronic obstructive pulmonary disease (COPD), atherosclerosis, asthma, and pancreatic cancer. Yishi Xie , Wenbin Kuang , Dawei Wang , Kai Yuan , Peng Yang Tags CXCR2 , CXCR2 antagonist , Cancer , Chronic obstructive pulmonary disease (COPD) , Coronavirus disease 2019 (COVID-19) , Inflammatory disease.
- Neuroimmune interplay during type 2 inflammation: symptoms, mechanisms and therapeutic targets in atopic diseases
The consequences of altered neuroimmune activity differ with tissue type and disease and include: skin and prurigo nodularis; airway inflammation/hyperresponsiveness, loss of expiratory volume, airflow obstruction adrenal medulla peptide 8-22 , Bullous pemphigoid , C-C motif chemokine ligand 17 , CCL17 , CGRP , CIU , COPD , CRSsNP , CRSwNP , CSF2 , CSU , Calcitonin gene-related peptide , Chronic idiopathic urticaria , Chronic obstructive pulmonary disease , Chronic rhinosinusitis with nasal polyps , Chronic rhinosinusitis without
- GPCRs and fibroblast heterogeneity in fibroblast-associated diseases
News < GPCRs in Oncology and Immunology GPCRs and fibroblast heterogeneity in fibroblast-associated diseases About one-third of the commercially available drugs for various diseases target the GPCRs. architecture of the GPCRs and their intertwined signaling in pathological conditions such as idiopathic pulmonary Understanding the dynamics of GPCR signaling in fibroblasts with disease progression can help in the recognition of the complex interplay of different GPCR subtypes in fibroblast-mediated diseases.