This comprehensive course is designed to provide an in-depth exploration of key concepts in pharmacology, offering a nuanced understanding of drug interactions and mechanisms of action. The curriculum is divided into four modules, each focusing on essential aspects of pharmacological principles. Whether you are a healthcare professional, researcher, or student in the life sciences, this course will enhance your knowledge and critical thinking skills in the field of pharmacology.

September 2022 High GPER expression in triple-negative breast cancer is linked to pro-metastatic pathways According to the cutoff value, 26.4% (95/360) of patients showed high GPER expression and significant In quantitative comparison, GPER abundance is correlated with the high-risk subtype of TNBC. Furthermore, univariate analysis confirmed that GPER was a significant prognostic factor for DMFS in Transcriptome-based bioinformatics analysis revealed that GPER was linked to pro-metastatic pathways

We’ve curated 10 GPCR papers, seven industry news, and two GPCR job ads! This week's highlight: Dr. Kathleen M Caron and her team studied the GPER/GPR30 complex with β1-adrenergic receptor and AKAP5 in GPCR University February 8 - 29: Join Dr. GPCR University's live course with Dr. Terry Kenakin. in Oncology and Immunology G protein-coupled estrogen receptor (GPER)/GPR30 forms a complex with the GPCR Ecosystem

GPCR activation typically occurs through the binding of agonists which stabilize receptor conformations GPCR targeting drugs: orthosteric vs allosteric sites Most of the drugs targeting GPCRs bind to the orthosteric GPCRs functional selectivity Recent research has revealed a more intricate understanding of GPCR behavior Agonist binding to GPCRs doesn't always trigger all associated events sequentially. selectively activate specific cellular outcomes linked to that GPCR.

The learning platform for the GPCR enthusiasm The Dr. informed in the world of GPCR. As a member, you can access: Dr.GPCR Podcast videos Live GPCR events Weekly classified GPCR news Contributor Private groups 30+ Symposia recorded talks GPCR Job listings GPCR Event listings Direct access to members The premium membership is priced at $24.99 per month or $249.99 per year.

GPCR Symposia Virtual - FREE - event series of 1-day. Provide more topic-specific events to the GPCR community All Symposia Events are: 1. Virtual 2. Networking GPCRs in Immunology and Oncology November 17, 2023 Details GPCRs as Therapeutic Modalities GPCR Activation and Signaling May 19, 2023 Details Recent Advances in Understanding Challenging GPCRs GPCR Strategic Partner