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9 items found for " Gnas"
Posts (6)
- 📰 GPCR Weekly News, March 6 to 12, 2023
GPCRs in Oncology and Immunology GPR176 Promotes Cancer Progression by Interacting with G Protein GNAS
- 📰 GPCR Weekly News
GPCRs in Cardiology, Endocrinology, and Taste Pathogenic variants of the GNAS gene introduce an abnormal
- 📰 GPCR Weekly News, January 29 to February 4, 2024
functional insight into the interaction of Clostridioides difficile toxin B and FZD7 Loss-of-function of GNAL
Other Pages (3)
- Proteogenomic landscape and clinical characterization of GH-producing pituitary adenomas/somatotroph pituitary neuroendocrine tumors
Targeted capture sequencing revealed GNAS as the only driver gene, as previously reported. ontology analysis was performed for differentially expressed proteins between wild-type and mutant GNAS The results suggested that GNAS mutations impact endocrinological features in acromegaly through GPCR These results identified a biological connection between GNAS mutations and the clinical and biochemical
- Wnt pathway inhibition with the porcupine inhibitor LGK974 decreases trabecular bone but not fibrosis in a murine model with fibrotic bone
of the bone is characterized by fibrotic, expansile bone lesions caused by activating mutations in GNAS fibrous dysplasia (FD) , osteoblasts , trabecular bone , G-protein coupled receptor signaling , GPCR , Gnas
- Comparative Analysis of the GNAI Family Genes in Glioblastoma through Transcriptomics and Single-Cell Technologies
< GPCR News < GPCRs in Oncology and Immunology Comparative Analysis of the GNAI Family Genes in Glioblastoma subunit 3 (GNAI3) and a poor prognosis. A single-cell analysis was used to assess GNAI3 expression in GBM. The results demonstrated that GNAI family genes, specifically GNAI3, were significantly associated with Our findings suggest that the GNAI3 gene holds potential as a prognostic biomarker for GBM.