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39 items found for " Hypomethylating agents"

Posts (21)

Adhesion GPCR Consortium Newsletter - May 2024
PMID: 38412860 GPR133 is hypomethylated and upregulated in decidual macrophages in recurrent spontaneous
Discovery On Target, October 17-20, 2022, Boston, USA
technologies, as well as target validation strategies for the discovery and development of novel therapeutic agents
Upregulation of Phospholipase C Gene Expression Due to Norepinephrine-Induced Hypertrophic Response
(PLC) is thought to have a key role in the cardiomyocyte response to several different hypertrophic agents

Spliceosome mutations are associated with clinical response in a phase 1b/2 study of the PLK1 inhibitor onvansertib in combination with decitabine in relapsed or refractory acute myeloid leukemia
Pamela S Becker , Tara L Lin , Sandra L Silberman , Eunice S Wang , Amer M Zeidan Tags AML , Biomarker , Hypomethylating agents , Onvansertib , PLK1 , Splicing Source Contribute to the GPCR News Coming soon Become a Contributor
GPR37 expression as a prognostic marker in gliomas: a bioinformatics-based analysis
Finally, hypomethylation of the GPR37 promoter was associated with its high expression levels and poor
In Silico Design of Novel RGS2-Galpha-q Interaction Inhibitors with Anticancer Activity
We sought to develop RGS2 inhibitors as potential chemotherapeutic agents utilizing structure-based drug These results highlight the potential RGS2 inhibitors have to be a new class of chemotherapeutic agents