Search Results
146 items found for " Ji'ou Gu"
Posts (81)
- N-terminal alterations turn the gut hormone GLP-2 into an antagonist with gradual loss of GLP-2 ...
October 2022 N-terminal alterations turn the gut hormone GLP-2 into an antagonist with gradual loss of interaction "Background and purpose: To fully elucidate the regulatory role of the GLP-2 system in the gut
- Community guidelines for GPCR ligand bias: IUPHAR review 32
Here, we provide guidelines and terminology for any scientists to design and report ligand bias experiments The guidelines will aid consistency and clarity, as the basic receptor research and drug discovery communities analytical methods are still evolving and should benefit from and contribute to the implementation of the guidelines
- Divergent roles for the gut intraepithelial lymphocyte GLP-1R in control of metabolism, microbiota..
September 2022 Divergent roles for the gut intraepithelial lymphocyte GLP-1R in control of metabolism , microbiota, and T cell-induced inflammation "Gut intraepithelial lymphocytes (IELs) are thought to Here, we show that the gut IEL GLP-1 receptor (GLP-1R) is not required for enteroendocrine L cell GLP Instead, the gut IEL GLP-1R is essential for the full effects of GLP-1RAs on gut microbiota. Such effects are mediated by the suppression of gut IEL effector functions linked to the dampening of
Other Pages (65)
- Prediction of survival and immunotherapy response by the combined classifier of G protein-coupled receptors and tumor microenvironment in melanoma
, Chenlu Wei , Tianyi Zhang , Yu Zhu , Jia Feng , Feng Qin , Yanwen Yang , Chuanyuan Wei , Jianying Gu
- Be Our Guest | Dr. GPCR Ecosystem
Be our Guest In each episode, we chat with an expert about their career trajectory, discoveries, and To be a guest, fill out the form below, and we’ll be in touch in 48 hours.
- G protein-coupled estrogen receptor (GPER)/GPR30 forms a complex with the β1-adrenergic receptor, a membrane-associated guanylate kinase (MAGUK) scaffold protein, and protein kinase A anchoring protein (AKAP) 5 in MCF7 breast cancer cells
estrogen receptor (GPER)/GPR30 forms a complex with the β1-adrenergic receptor, a membrane-associated guanylate their C-terminal tails through which they interact in the plasma membrane with membrane-associated guanylate