), an organ-specific chemokine receptor, interacts with its exclusive ligand CCL25 to promote tumor proliferation In vitro , SACC cell proliferation and apoptosis were evaluated using Cell Counting Kit-8 and colon formation

They have participated in various cellular processes such as cell proliferation, migration, apoptosis

protein-coupled receptor kinase 2 is essential to enable vasoconstrictor-mediated arterial smooth muscle proliferation arterial contraction and stimulates signalling pathways that promote vascular smooth muscle cell (VSMC) proliferation GPCR signalling through phosphoinositide 3-kinase (PI3K)/protein kinase B (Akt) promotes VSMC proliferation implicated in controlling various aspects of cellular growth, we examined whether GRK2 could affect VSMC proliferation These data suggest GRK2 expression is essential to facilitate vasoconstrictor-driven VSMC proliferation

< GPCR News < GPCRs in Oncology and Immunology RGS20 promotes non-small cell lung carcinoma proliferation CCK8 and cell cloning were conducted to determine the proliferation ability of H1299 and Anip973 cells In vitro and in vivo experiments verified whether overexpression of RGS20 affect the proliferation and Further, RGS20 accelerated cell proliferation by increasing autophagy. Conclusion: Our findings indicate that RGS20 drives NSCLC cell proliferation by triggering autophagy

The study explored the influence of GPR37 on tumor cell proliferation. prognosis. (2) It was demonstrated that GPR37 positively regulates NSCLC cell invasion, migration, and proliferation Conversely, we observed that GPR37 knockdown suppresses NSCLC cell invasion, migration, and proliferation

an agonist of GPR97, attenuated the psoriasis-like skin disease and restricted HaCaT cells abnormal proliferation this adhesion receptor may affect immune cell enrichment and function in skin and alter keratinocytes proliferation