The cleavage appears to occur at an atypical GPCR proteolysis site within the GAIN domain during an early The products, i.e., the N-terminal and C-terminal fragments, seem to remain associated after self-proteolysis

during their synthesis in the endoplasmic reticulum, many of these receptors are cleaved at the GPCR Proteolysis structures showed how the Stalk region, which is a short peptide released from the GAIN during auto-proteolysis

October 2022 "Protease-activated receptor 2 (PAR2) is a G-protein-coupled receptor (GPCR) activated by proteolytic

Furthermore, proteases have an integral role in cell proliferation and growth because the proteolysis

Van Meir Site Specific N-Glycosylation Of The N-Terminal Fragment Of ADGRG6 Drives Proteolytic Processing on the web Google Scholar Site Specific N-Glycosylation Of The N-Terminal Fragment Of ADGRG6 Drives Proteolytic

Hence, Remo is proteolytically processed, either by the GAIN domain or an alternative protease that cleaved