Deep mutational scanning (DMS) is a powerful method for studying the functional consequences of various Instead, a collection of titratable residues spans from the extracellular surface to the transmembrane Deep mutational scanning: assessing protein function on a massive scale. Measuring the activity of protein variants on a large scale using deep mutational scanning. Predicting Drug Resistance Using Deep Mutational Scanning.

This Week’s Highlights: Harnessing Deep Mutational Scanning for Enhanced Drug Discovery Cam Sinh Lu GPCR-BSD: a database of binding sites of human G-protein coupled receptors under diverse states Fan Liu , Han Zhou , Xiaonong Li , Liangliang Zhou , Chungong Yu , Haicang Zhang , Dongbo Bu 🤩 Seriously, why would

He has led teams that have filed more than 10 Investigational New Drug Applications (IND), as well as In 2007 he formed IndiPharm which was a full-service Contract Research Organization whose operational He received his undergraduate Bachelor of Science Degree in Pharmacy from The Philadelphia College of He went on to study medicine at the Royal College of Surgeons in Ireland before receiving his Medical

Authors Jie Xiong , Yu-Ting Dai , Wen-Fang Wang , Hao Zhang , Chao-Fu Wang , Tong Yin , Shu Cheng , Hui-Juan Zhong , Shan-He Yu , Lu Jiang , Sheng-Yue Wang , Hai Fang , Rui-Hong Zhang , Yue Zhu , Hong-Mei Yi ,

He also directs a collaborative neuroscience R&D program with Servier (France) and is the co-founder company (2009-2012), where he was responsible all of the company’s discovery biology. He is an acknowledged expert in drug discovery, particularly in the field of psychiatry, where he has He has a degree and PhD in pharmacology from Queens' College, Cambridge and University College London He is also a corresponding member of NC-IUPHAR.

For postdoctoral training, he joined the laboratory of Dr. Strosberg AD in France, where he worked on the regulation of ß-adrenergic receptors. He is the Research director at INSERM with a specific interest in G protein-coupled receptors by developing He showed the formation of melatonin receptor heteromers in vitro and in vivo and their importance in He is a highly cited researcher – 2019 and 2020 identified by Clarivate Web of Science ™. Dr.