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The resulting NETs presumably activate platelets and coagulation factors, further contributing to the

September 2022 Sweet taste receptor agonists attenuate macrophage IL‐1β expression and eosinophilic inflammation linked to autophagy deficiency in myeloid cells "Background Eosinophilic inflammation is a hallmark

September 2022 GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome Here we demonstrate that GPR84 is highly upregulated in inflamed colon tissues of active ulcerative colitis These results define a unique role of GPR84 in innate immune cells and intestinal inflammation, and suggest

efferocytic clearance of apoptotic cells to facilitate intercellular communication and promote the resolution of inflammation. However, whether inflammation resolution is modulated by extracellular vesicles (EVs) and vesicular mediators of inflammation. Neutralization and knockdown of prosaposin or blocking GRP37 abrogates the pro-resolution effects of

GPCRs in Oncology and Immunology Ultrasensitive dose-response for asbestos cancer risk implied by new inflammation-mutation A recent Inflammation Somatic Mutation (ISM) theory of cancer posits instead that tissue-damage-associated inflammation that epigenetically recruits, activates and orchestrates stem cells to engage in tissue resolution (e.g., by doing so for GPCR-mediated signal transduction by one or more endogenous autacoid Author Kenneth T Bogen Tags Asbestos , Cytotoxicity , Inflammation , Lung cancer , Mesothelioma , Mutation

< GPCR News < GPCRs in Oncology and Immunology Itaconate in host inflammation and defense Published date March 5, 2024 Abstract "Immune cells undergo rapid and extensive metabolic changes during inflammation