October 2022 GPR15 expressed in T lymphocytes from RA patients is involved in leukocyte chemotaxis to

, mainly activated by interleukin 8 (IL-8 or CXCL8), are expressed in a variety of cells including, leukocytes currently being directed towards CXCR1/2 inhibitors, as these receptors primarily induce the chemotaxis of leukocytes

, mainly activated by interleukin 8 (IL-8 or CXCL8), are expressed in a variety of cells including, leukocytes currently being directed towards CXCR1/2 inhibitors, as these receptors primarily induce the chemotaxis of leukocytes

missing comprehensive studies comparing the role of this GRK interplay for (a) multiple GPCRs within one leukocyte study shows that combinatorial depletions of GRKs have pleiotropic and cell-type specific effects in leukocytes demonstrate the complexity of GRK functions in immune cells, which go beyond GPCR desensitization in specific leukocyte the need for studying GRK functions in primary immune cells to address their specific roles in each leukocyte Tags B cells; G-protein coupled receptors; GRK; T cells; dendritic cells; immune cell trafficking; leukocytes

< GPCRs in Oncology and Immunology GPR15 expressed in T lymphocytes from RA patients is involved in leukocyte

nomenclature for chemokine receptors that are categorized into a large subgroup of G protein–coupled (GPCR) leukocyte