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1032 items found for " pH-GPCR"

Programs (7)

  • GPCRs in Pharmacology

    This comprehensive course is designed to provide an in-depth exploration of key concepts in pharmacology, offering a nuanced understanding of drug interactions and mechanisms of action. The curriculum is divided into four modules, each focusing on essential aspects of pharmacological principles. Whether you are a healthcare professional, researcher, or student in the life sciences, this course will enhance your knowledge and critical thinking skills in the field of pharmacology.

  • Dr. GPCR Ecosystem 2.0

    GPCR Ecosystem.

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Posts (576)

  • PH-Binding Motif in PAR4 Oncogene: From Molecular Mechanism to Drug Design

    October 2022 "While the role of G-protein-coupled receptors (GPCR) in cancer is acknowledged, their underlying Protease-activated receptors (PAR), a subgroup of GPCRs, form a family of four members (PAR1-4) centrally Here, we demonstrate identification of a pleckstrin-homology (PH)-binding motif within PAR4, critical In addition to PH-Akt/PKB association, other PH-containing signal proteins such as Gab1 and Sos1 also Read more at the source #DrGPCR #GPCR #IndustryNews

  • GPCRs are not simple on-off switches: deep dive into GPCR-ligand interactions

    GPCR activation typically occurs through the binding of agonists which stabilize receptor conformations GPCR targeting drugs: orthosteric vs allosteric sites Most of the drugs targeting GPCRs bind to the orthosteric GPCRs functional selectivity Recent research has revealed a more intricate understanding of GPCR behavior Agonist binding to GPCRs doesn't always trigger all associated events sequentially. selectively activate specific cellular outcomes linked to that GPCR.

  • Exploring the Breakthroughs in GPCR Research

    📰 GPCR Weekly News, July 8 to 14, 2024 Hello readers! Check out our GPCR coverage for this week. We have 15 GPCR papers, three industry news, and two job ads.   GPCR Event Highlight 11th Adhesion GPCR Workshop Hosted by the Adhesion GPCR Consortium, this event Let’s dive into the   Classified GPCR News  from July 8th to 14th, 2024 GPCR Activation and Signaling GPCR Ecosystem

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Other Pages (448)

  • GPR4 in the pH-dependent migration of melanoma cells in the tumor microenvironment

    < GPCR News < GPCRs in Oncology and Immunology GPR4 in the pH-dependent migration of melanoma cells in Membrane-bound receptors, such as the proton-sensitive GPCR (pH-GPCR) GPR4, are considered as potential Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology

  • Involvement of Protease-Activated Receptor2 Pleckstrin Homology Binding Domain in Ovarian Cancer: Expression in Fallopian Tubes and Drug Design

    < GPCR News < GPCRs in Oncology and Immunology Involvement of Protease-Activated Receptor2 Pleckstrin for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs , and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs into GPCR function GPCR Activation and Signaling More from Dr. GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

  • GPR68-ATF4 signaling is a novel prosurvival pathway in glioblastoma activated by acidic extracellular microenvironment

    < GPCR News < GPCRs in Oncology and Immunology GPR68-ATF4 signaling is a novel prosurvival pathway in News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

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