Ecosystem
Beta Site
Search Results
17 items found for "ADME"
- Mechanistic exploration of bioactive constituents in Gnetum gnemon for GPCR-related cancer treatment through network pharmacology and molecular docking
Poolpirom, Oranan Pantanakong, Pitchaporn Chumworadet, Fumitaka Kawakami, Motoki Imai, Aman Tedasen Tags ADME
- Ep 148 with Dr Arthur Christopoulos
They also shared their admiration for the work of a mutual friend and discussed the history of muscarinic funding system in Australia, the importance of impact in research, and the challenges of balancing administrative
- Ep 146 with Dr Michael Feigin
Mike reflected on his early years as a postdoc, admitting that he lacked focus and didn't see the direct
- Ep 154 with Dr Badr Sokrat
competition in their home province, Quebec, and its impact on students' mental health and university admission scientists, particularly students and researchers, face, such as imposter syndrome, constant pressure from administrative
- GPCR Retreat 2023 - Part I
This work was made possible by the optimization of longitudinal intravenous self-administration paradigms
- Ep 149 with Dr Arthur Christopoulos
They also shared their admiration for the work of a mutual friend and discussed the history of muscarinic funding system in Australia, the importance of impact in research, and the challenges of balancing administrative
- Ep 82 with Dr. Lauren M. Slosky
This work was made possible by the optimization of longitudinal intravenous self-administration paradigms
- Structural Basis for the Recognition of GPRC5D by Talquetamab, a Bispecific Antibody for Multiple Myeloma
Talquetamab, a Food and Drug Administration-approved T-cell-directing bispecific antibody developed for
- Exploiting frequent and specific expression of PRL3 in pediatric solid tumors for first-in-child use of PRL3-zumab humanized antibody
PRL3-zumab, a first-in-class humanized antibody, was administered in a dose escalation schedule in a A 28.6% reduction in maximum target lesion diameter was achieved when PRL3-zumab was administered concurrently
- Pancreatic ductal adenocarcinoma, β-blockers and antihistamines: A clinical trial is needed
opine and propose that an urgent clinical trial is needed to determine if repurposing these two orally administered
- Efferocytes release extracellular vesicles to resolve inflammation and tissue injury via prosaposin-GPR37 signaling
Administration of efferocyte-derived EVs in a murine model of atherosclerosis is associated with an increase
- Exacerbating effects of single-dose acute ethanol exposure on neuroinflammation and amelioration by GPR110 (ADGRF1) activation
immune cells cooperatively ameliorates neuroinflammation caused by systemic lipopolysaccharide (LPS) administration
- Session VI | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
In vivo intratumoral administration of the ADC in patient-derived GBM xenografts in the brain of immunodeficient
- Neuroimmune interplay during type 2 inflammation: symptoms, mechanisms and therapeutic targets in atopic diseases
potential cation channel subfamily M member 8 , Transient receptor potential vanilloid 1 , US Food and Drug Administration
- Itaconate in host inflammation and defense
Administration of ITA protects against inflammatory diseases and blockade of ITA production enhances
- Exploration of prognostic and treatment markers in hepatocellular carcinoma via GPCR-related genes analysis
family of signaling receptors, account for 34 % of all the drug targets approved by the Food and Drug Administration
- Metallo-protease Peptidase M84 from Bacillusaltitudinis induces ROS-dependent apoptosis in ovarian cancer cells by targeting PAR-1
In in vivo set-up, weekly intraperitoneal administration of Peptidase M84 in syngeneic mice significantly
