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40 items found for "Adam S Sperling"
- Respiratory infections predominate after day 100 following B-cell maturation antigen-directed CAR T-cell therapy
Authors Jessica S Little , Megha Tandon , Joseph Seungpyo Hong , Omar Nadeem , Adam S Sperling , Noopur
- Ep 119 with Tanishka S. Saraf
GPCR Podcast << Back to podcast list Tanishka S. Saraf About Tanishka S. neurobiology of neuropsychiatric disorders and to develop safe and effective treatments. " Tanishka S.
- Ep 38 with Dr. Alexander S. Hauser
Alexander S. Hauser About Dr. Alexander S. Alexander S.
- In Silico Design of Novel RGS2-Galpha-q Interaction Inhibitors with Anticancer Activity
Authors Adam Bair, Natalie Printy, So Hee Choi, Joshua Wilkinson, Joseph O'Brien, Brian Myers, David
- Session VIII * | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Bayonas Abstract "All animals develop through the recognition, adhesion, and fusion of a differentiated sperm Additionally, the bacterium Vibrio fischeri also induces mating in S. rosetta cultures, suggesting that adhesion GPCR, named Cupidon, that regulates the switch from vegetative growth to sexual reproduction in S. Together, our results suggest that Cupidon prevents sexual reproduction in S. rosetta under high nutrient
- The β2-adrenergic receptor associates with CXCR4 multimers in human cancer cells
Jo , Yong Bhum Song , Chulo Park , Piotr Zalicki , Jae-Yeon Jeong , Won-Ki Huh , Niña G Caculitan , Adam
- Ep 107 with Dr. Roger Sunahara
G protein splice forms, specifically the short and long forms of the stimulatory G protein, Galpha-s( s) and Galpha-s(l), respectively. We demonstrated that Galpha-s(l), but not Galpha-s(s), regulates extracellularly regulated kinases (ERK We speculate that these aberrations in Galpha-s(l), specifically, may be involved in other pathologies
- Deciphering the genetic landscape of lumpy skin disease: Unraveling variable virulence through comprehensive genome sequence analysis in India
Authors R Mishra, S K Biswas, S Nandi, S Mahajan, K G Sai Balaji, V Gairola, D Poloju, S Gulzar, K P
- Blockade of vasoactive intestinal peptide receptor 2 (VIPR2) signaling suppresses cyclin D1-dependent cell-cycle progression in MCF-7 cells
The percentage of cells in the S-M phase was decreased in MCF-7 cells treated with KS-133. MEK) inhibitor U0126 and the class I PI3K inhibitor ZSTK474 decreased the percentage of cells in the S KS-133 reduced the percentage of cells in the S phase more than treatment with U0126 or ZSTK474 alone regulates cyclin D1 levels through the cAMP/PKA/ERK and PI3K/AKT/GSK3β pathways, and mediates the G1/S
- The GPCR-Gαs-PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure
The Author(s), under exclusive licence to Springer Nature America, Inc." Authors Victoria H Wu , Bryan S Yung , Farhoud Faraji , Robert Saddawi-Konefka , Zhiyong Wang , Alexander T Wenzel , Miranda J Song , Meghana S Pagadala , Lauren M Clubb , Joshua Chiou , Sanju Sinha , Marin Matic , Francesco Raimondi , Thomas S Hoang , Rebecca Berdeaux , Dario A A Vignali , Ramiro Iglesias-Bartolome
- Phase 1/2 study of sorafenib added to cladribine, high-dose cytarabine, G-CSF, and mitoxantrone in untreated AML
Othus , Kelsey-Leigh A Garcia , Mary-Elizabeth M Percival , Ryan D Cassaday , Vivian G Oehler , Pamela S Becker , Jacob S Appelbaum , Janis L Abkowitz , Johnnie J Orozco , Siobán B Keel , Paul C Hendrie , Bart
- Ep 130 with Dr. Richard Premont
Harrington Discovery Institute and Case Western Reserve University, where he studies GPCR regulation by S-nitrosylation by GIT/PIX scaffolding complexes during cellular signaling, and characterizing the role of protein S-nitrosylation
- Ep 131 with Dr. Richard Premont
Harrington Discovery Institute and Case Western Reserve University, where he studies GPCR regulation by S-nitrosylation by GIT/PIX scaffolding complexes during cellular signaling, and characterizing the role of protein S-nitrosylation
- Ep 132 with Dr. Richard Premont
Harrington Discovery Institute and Case Western Reserve University, where he studies GPCR regulation by S-nitrosylation by GIT/PIX scaffolding complexes during cellular signaling, and characterizing the role of protein S-nitrosylation
- Ep 133 with Dr. Richard Premont
Harrington Discovery Institute and Case Western Reserve University, where he studies GPCR regulation by S-nitrosylation by GIT/PIX scaffolding complexes during cellular signaling, and characterizing the role of protein S-nitrosylation
- Ep 09 with Lauren Celano
GPCR podcast episode, we sat down to chat with Lauren Celano to talk about career options for Ph.D.’s.
- Spliceosome mutations are associated with clinical response in a phase 1b/2 study of the PLK1 inhibitor onvansertib in combination with decitabine in relapsed or refractory acute myeloid leukemia
Authors Peter J P Croucher , Maya Ridinger , Pamela S Becker , Tara L Lin , Sandra L Silberman , Eunice S Wang , Amer M Zeidan Tags AML , Biomarker , Hypomethylating agents , Onvansertib , PLK1 , Splicing
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- Ep 111 with Chloe Hicks
previous endeavors involved exploring the effect of subcellular location on the signaling profile of CXCR3’s
- Using food perception and bioamine signaling networks to slow aging
Miller 1, Shijiao Huang 1, Elizabeth S. Dean 1, and Scott F. Leiser 1 1.
- Ep 88 with Dr. Hannes Schihada
council) PostDoc fellowship to Stockholm, Sweden, in order to focus my research on class Frizzled GPCR s
- Ep 139 with Dr Silvia Sposini
regulatory mechanisms of GPCR action, namely dimerization and membrane trafficking, in Dr Aylin Hanyaloglu 's
- GprC of the nematode-trapping fungus Arthrobotrys flagrans activates mitochondria and reprograms fungal cells for nematode hunting
Authors Xiaodi Hu, David S Hoffmann, Mai Wang, Lars Schuhmacher, Maria C Stroe, Birgit Schreckenberger
- A virally encoded GPCR drives glioblastoma through feed-forward activation of the SK1-S1P1 signaling axis
Bergkamp , Jeffrey R van Senten , Hendrik J Brink , Maarten P Bebelman , Jelle van den Bor , Tuğçe S
- Mutation Patterns Predict Drug Sensitivity in Acute Myeloid Leukemia
Aguilar, Lauren Hagen, Jeannine McCune, Richard Gelinas, Raymond J Monnat Jr, Ilya Shmulevich, Pamela S
- LP2, a cyclic angiotensin-(1-7) analog extended with an N-terminal D-lysine, impairs growth of patient-derived xenografts of colorectal carcinoma in mice
and, together with its excellent specificity, safety and stability, warrant further evaluation of LP2's
- Deletion of macrophage Gpr101 disrupts their phenotype and function dysregulating host immune responses in sterile and infectious inflammation
Authors Magdalena B Flak , Duco S Koenis , Maria Gonzalez-Nunez , Ana Chopo-Pizarro , Jesmond Dalli Tags
- Severity of neurological long-COVID symptoms correlates with increased level of autoantibodies targeting vasoregulatory and autonomic nervous system receptors
Authors Felix S Seibert , Ulrik Stervbo , Lea Wiemers , Sarah Skrzypczyk , Maximillian Hogeweg , Sebastian