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74 items found for "Affiong Ika Oqua"

Programs (1)

Applying Pharmacology to Drug Discovery
Techniques will be described to quantify drug activity in terms of affinity, efficacy, and allosteric

📰 GPCR Weekly News, May 6 to 12, 2024
Gutkind, and Francesco Raimondi for their work on The landscape of cancer-rewired GPCR signaling axes Affiong Ika Oqua, Dr.
Label-free LC-MS based assay to characterize small molecule compound binding to cells
this assay was applied to an ion channel target with its agonists, of which the determined binding affinity
Membrane Lipids Are an Integral Part of Transmembrane Allosteric Sites in GPCRs: A Case Study of...
The observed differences in the binding affinity and cooperativity arise from the functional groups that membrane lipids as an integral component of transmembrane sites for accurate characterization, binding-affinity

Principles of Pharmacology in Drug Discovery I | Dr. GPCR Ecosystem
Registrants will learn: Essentials of measuring pharmacologic activity of ligands (affinity, efficacy Lecture 2: Drug Affinity: Measurement of Antagonism (Binding and Function) / Classifying Antagonists.
The Effect of Cancer-Associated Mutations on Ligand Binding and Receptor Function - A Case for the 5-HT2C Receptor
We found that the affinity of the endogenous agonist serotonin (5-HT) and inverse agonist mesulergine In contrast, 5-HT displayed higher affinity at E306K6.30 and E306A6.30, while a trend of decreased efficacy
Molecular docking and dynamics simulation studies uncover the host-pathogen protein-protein interactions in Penaeus vannamei and Vibrio parahaemolyticus
Hence, this study was conducted to identify the interaction sites and binding affinity between several Potential interaction sites and the binding affinity between host and pathogen proteins were identified