April 2022 Ono Enters into Collaboration Agreement with Domain Therapeutics and Université de Montréal (Strasbourg, France; CEO: Pascal Neuville ; “Domain”) and Université de Montréal (Québec, Canada; “UdM

Tim De Groof! It’s not often when you get the best of both worlds - nano-bodies and #GPCRs.

the Department of Biochemistry and Molecular Medicine of the Faculty of Medicine of the Université de

Constitutive, Basal, and β-Alanine-Mediated Activation of the Human Mas-Related G Protein-Coupled Receptor By stimulating human MRGPRD-expressing HeLa cells with the agonist β-alanine, we observed a release of IL-6. β-alanine-induced signaling through MRGPRD was investigated further by probing downstream signaling Consequently, the dynamic range for IL-6 detection as an assay for β-alanine-mediated activation of MRGPRD

Member Profile Antony Boucard Professor Centro de Investigación y de Estudios Avanzados del IPN (Cinvestav AB: Favorite Taco: Taco de suadero (pronounced swa-day-ro), fatty, with meat caramelized in its own fat

Dimerization: Unveiling Its Role in Receptor Function and Signaling Sonja Peter , Brian Bender , Chris De

De novo drug design: AI algorithms can generate new molecules with desired properties, such as binding chemical space, limiting their ability to identify truly novel chemotypes”(Thomas, Smith, O’Boyle, de

Domain Therapeutics was nominated for the Trophée de l'Innovation Technologique (Technological Innovation

Therefore, matching a ligand to an orphan GPCRs, the process of de-orphanizing, is of great importance

Michel Bouvier received the title of Doctor Honoris Causa from the Université de Montpellier Domain Therapeutics

This week's highlight includes congrats to Omolade Otun , Chris de Graaf , Cherine Bechara , et al.

This week's highlight includes congrats to: Tessa de Vries, Graham Ladds, Antoinette MaassenVanDenBrink

ended 31 December 2022 Addex Raises $5.0 Million in Equity Financing Testing the limits of SMILES-based de

., Rodríguez De Fonseca, F., Puente, N., Marsicano, G., & Grandes, P. (2016).

In the prospect of a psychedelic drug becoming again an approved treatment, much of these efforts have

From outside to inside and back again: the lysophosphatidic acid-CCN axis in signal transduction.

pathophysiology and treatment of CNS disorders GPCRs in Oncology and Immunology From outside to inside and back again

We're partnering again with the 3rd GPCRs - Targeted Drug Discovery Summit in Boston on March 5-7, 2024

GPCR Partnered Events March 5 - 7, 2024 | 3rd GPCRs - Targeted Drug Discovery Summit  We're partnering again

We will be offering this live course again later this year.