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38 items found for "Amer M Zeidan"
- Spliceosome mutations are associated with clinical response in a phase 1b/2 study of the PLK1 inhibitor onvansertib in combination with decitabine in relapsed or refractory acute myeloid leukemia
J P Croucher , Maya Ridinger , Pamela S Becker , Tara L Lin , Sandra L Silberman , Eunice S Wang , Amer M Zeidan Tags AML , Biomarker , Hypomethylating agents , Onvansertib , PLK1 , Splicing Source Contribute
- Ep 82 with Dr. Lauren M. Slosky
Lauren M. Slosky About Dr. Lauren M. Lauren M.
- G Protein-coupled Receptor-mediated Membrane Targeting of PLCγ2 is Essential for Neutrophil Chemotaxis
PLCγ2 plays an essential role in neutrophil chemotaxis. " Authors Xuehua Xu , Xi Wen , Smit Bhimani , Amer
- Identification of S1PR4 as an immune modulator for favorable prognosis in HNSCC through machine learning
to cladribine, high-dose cytarabine, granulocyte colony-stimulating factor, and mitoxantrone (CLAG-M) Comparing outcomes using CLAG-M/sorafenib with those of a matched cohort of 76 patients treated with CLAG-M alone, multivariable-adjusted survival estimates were improved for 41 patients receiving CLAG-M These data suggest that CLAG-M/sorafenib is safe and improves OS and EFS relative to CLAG-M alone, with
- Ep 103 with Dr Kathleen Caron
Kathleen Caron About Kathleen M. Caron Kathleen M. Caron, Ph.D. is the Frederik L. Kathleen M.
- Protease-Activated Receptor-1 IgG Autoantibodies in Patients with COVID-19
Anne-Christin Beatrice Wilde, Pegah Ramezani Rad, Wolfgang Poller, Erik Asmus, Szandor Simmons, Wolfgang M Kuebler, Martin Witzenrath, Lajos Markó, Kai Jakobs, Marianna Puccini, David M Leistner, Ursula Rauch-Kröhnert
- Increased protease-activated receptor 1 autoantibodies are associated with severe COVID-19
Authors Florian Tran , Danielle M M Harris , Alena Scharmacher , Hanna Graßhoff , Kristina Sterner ,
- Pan-cancer functional analysis of somatic mutations in G protein-coupled receptors
Overall, this study presents a list of GPCRs that are amenable to experimental follow up to elucidate Authors Bongers B J , Gorostiola González M , Wang X , van Vlijmen HWT , Jespers W , Gutiérrez-de-Terán
- Neuroimmune interplay during type 2 inflammation: symptoms, mechanisms and therapeutic targets in atopic diseases
NGF , NMU , NP , Na(v) , Nasal polyps , Nerve growth factor , Neuromedin U , OSM , OSMRβ , Oncostatin M , Oncostatin-M specific receptor subunit beta , PAR2 , PC(20) , PN , Protease activated receptor 2 , potential , Transient receptor potential ankyrin 1 , Transient receptor potential cation channel subfamily M member 4 , Transient receptor potential cation channel subfamily M member 8 , Transient receptor potential
- Phase 1/2 study of sorafenib added to cladribine, high-dose cytarabine, G-CSF, and mitoxantrone in untreated AML
Authors Anna B Halpern , Eduardo Rodríguez-Arbolí , Megan Othus , Kelsey-Leigh A Garcia , Mary-Elizabeth M S Appelbaum , Janis L Abkowitz , Johnnie J Orozco , Siobán B Keel , Paul C Hendrie , Bart L Scott , M
- Delivery of US28 by incoming HCMV particles rapidly attenuates Akt activity to suppress HCMV lytic replication in monocytes
Authors Jamil Mahmud, Brittany W Geiler, Juthi Biswas, Michael J Miller, Julia E Myers, Stephen M Matthews , Amanda B Wass, Christine M O'Connor, Gary C Chan Source Contribute to the GPCR News Coming soon Become
- Identification of a G-protein coupled receptor-related gene signature through bioinformatics analysis to construct a risk model for ovarian cancer prognosis
The predictive ability of the model was evaluated by Kaplan-Meier (K-M) survival analysis. K-M analysis of the prognostic model showed that it could differentiate high- and low-risk patients,
- G protein-coupled estrogen receptor (GPER)/GPR30 forms a complex with the β1-adrenergic receptor, a membrane-associated guanylate kinase (MAGUK) scaffold protein, and protein kinase A anchoring protein (AKAP) 5 in MCF7 breast cancer cells
Authors Julia Tutzauer , D Stephen Serafin , Tobias Schmidt , Björn Olde , Kathleen M Caron , L M Fredrik
- Ep 75 with Vaithish Velazhahan
mechanisms of flavonoids in cancer using nuclear magnetic resonance spectroscopy (NMR) led to a Barry M.
- Chemokine N-terminal-derived peptides differentially regulate signaling by the receptors CCR1 and CCR5
Walser , Stavroula Louka , Ida Aaberg Lillethorup , Jon Våbenø , Katrine Qvortrup , Paul Proost , Mette M
- Interaction with the cell adhesion molecule NEGR1 affects mGluR5 cell signalling
signalling Date & Time Friday, November 3rd / 1:30 PM Abstract Coming Soon About Fabiola Ribeiro "Fabiola M.
- Leukotriene B4 receptor 2 governs macrophage migration during tissue inflammation
Authors Ebru Ermis , Titli Nargis , Kierstin Webster , Sarah A Tersey , Ryan M Anderson , Raghavendra
- Blockade of vasoactive intestinal peptide receptor 2 (VIPR2) signaling suppresses cyclin D1-dependent cell-cycle progression in MCF-7 cells
The percentage of cells in the S-M phase was decreased in MCF-7 cells treated with KS-133.
- In Silico Design of Novel RGS2-Galpha-q Interaction Inhibitors with Anticancer Activity
Bair, Natalie Printy, So Hee Choi, Joshua Wilkinson, Joseph O'Brien, Brian Myers, David Roman, Tarek M
- The GPCR-Gαs-PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure
Saddawi-Konefka , Zhiyong Wang , Alexander T Wenzel , Miranda J Song , Meghana S Pagadala , Lauren M
- Purinergic GPCR-integrin interactions drive pancreatic cancer cell invasion
Qiaoying Wang , Edward Philip Carter , Nicolas Jaime Roth , Jessica Gibson , Ariana Samadi , Hemant M
- "Have a nice weekend, and I'll see you tomorrow!": RAMP-interacting GPCR Pathways
Time Thursday, November 2nd / 4:30 PM Keynote Talk Abstract Coming Soon About Kathleen Caron "Kathleen M.
- Pharmacological inhibition of neuropeptide Y receptors Y1 and Y5 reduces hypoxic breast cancer migration, proliferation, and signaling
Authors Sydney A Pascetta , Sarah M Kirsh , Makenna Cameron , James Uniacke .
- Distinct Activation Mechanisms of CXCR4 and ACKR3 Revealed by Single-Molecule Analysis of their Conformational Landscapes
Authors Christopher T Schafer, Raymond F Pauszek 3rd, Martin Gustavsson, Tracy M Handel, David P Millar
- Systems Pharmacodynamic Model of Combination Gemcitabine and Trabectedin in Pancreatic Cancer Cells. Part II: Cell Cycle, DNA Damage Response, and Apoptosis Pathways
Authors Xin Miao , Gilbert Koch , Shichen Shen , Xue Wang , Jun Li , Xiaomeng Shen , Jun Qu , Robert M
- Comparison of infectious complications with BCMA-directed therapies in multiple myeloma
Rose Tan, Malin Hultcrantz, Sergio A Giralt, Saad Z Usmani, Zainab Shahid, Sham Mailankody, Alexander M
- Combinatorial depletions of G-protein coupled receptor kinases in immune cells identify pleiotropic and cell type-specific functions
Authors Katharina M Glaser, Teresa K Tarrant, Tim Lämmermann Tags B cells; G-protein coupled receptors
