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September 2022 β2-Adrenergic Receptor Expression and Intracellular Signaling in B Cells Are Highly Dynamic In the past, treatment of arthritic B cells with a β2-adrenergic receptor (β2-ADR) agonist has been shown In this study, the expression and signaling of β2-ADR in B cells during collagen-induced arthritis (CIA ) were investigated to provide an explanation of why only B cells from arthritic mice are able to improve Splenic B cells were isolated via magnetic-activated cell sorting (MACS).

October 2022 Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent epithelial-cell-derived antimicrobial peptides defensins activated orphan G-protein-coupled receptors (GPCRs) Mrgpra2a/b generated mutant mouse lines lacking the entire Defensin (Def) gene cluster in keratinocytes or Mrgpra2a/b.

October 2022 Focusing on the role of secretin/adhesion (Class B) G protein-coupled receptors in placental Among them, the secretin/adhesion (Class B) G protein-coupled receptors are essential drug targets for Given the great value of the secretin/adhesion (Class B) G protein-coupled receptors in the regulation

Authors Anna B Halpern , Eduardo Rodríguez-Arbolí , Megan Othus , Kelsey-Leigh A Garcia , Mary-Elizabeth Vivian G Oehler , Pamela S Becker , Jacob S Appelbaum , Janis L Abkowitz , Johnnie J Orozco , Siobán B Keel , Paul C Hendrie , Bart L Scott , M Cristina Ghiuzeli , Elihu H Estey , Roland B Walter Source Contribute

News < GPCRs in Oncology and Immunology Respiratory infections predominate after day 100 following B-cell therapy Published date September 26, 2023 Abstract "Infections are an important complication after B-cell

Authors Olav Larsen , Sara Schuermans , Anna Walser , Stavroula Louka , Ida Aaberg Lillethorup , Jon