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11 items found for "Aurélien Rizk"
- Focusing on the role of secretin/adhesion (Class B) G protein-coupled receptors in placental...
hypertension and proteinuria, with a worldwide incidence of 3–8% and high maternal mortality, is a risk Obesity, immunological diseases and endocrine metabolic diseases are high-risk factors for the development
- 📰 GPCR Weekly News, July 31 to August 6, 2023
intracellular agonist Conserved class B GPCR activation by a biased intracellular agonist The psychosis risk fibroblast heterogeneity in fibroblast-associated diseases Ultrasensitive dose-response for asbestos cancer risk Molecule Medicines Targeting G Protein-Coupled Receptors Novo Nordisk A/S: Semaglutide 2.4 mg reduces the risk
- GPCRs are not simple on-off switches: deep dive into GPCR-ligand interactions
Those include the risk of unintended off-target effects, limited selectivity due to closely related receptor A third advantage is that they offer the prospect of reducing the risk of overdose, given that their effects, allowing for the administration of substantial doses of allosteric modulators with a diminished risk
- APEX2/AUR Biosensor: A Powerful Tool for Protein Interaction and Trafficking
insights gained from this research could inform the development of safer analgesics that minimize the risk
- 📰 GPCR Weekly News, April 22 to 28, 2024
. for their work on the Dysfunction of the adhesion GPCR latrophilin 1 (ADGRL1/LPHN1) increases the risk GPCRs Dysfunction of the adhesion G protein-coupled receptor latrophilin 1 (ADGRL1/LPHN1) increases the risk
- High GPER expression in triple-negative breast cancer is linked to pro-metastatic pathways and...
In quantitative comparison, GPER abundance is correlated with the high-risk subtype of TNBC.
- Targeting Intracellular Allosteric Sites in GPCRs
A third advantage is that they offer the prospect of reducing the risk of overdose, given that their effects, allowing for the administration of substantial doses of allosteric modulators with a diminished risk
- 📰 GPCR Weekly News, October 16 to 22, 2023
biotherapeutic drug discovery Novartis Kisqali® NATALEE analysis reinforces consistent reduction in risk
- 📰 GPCR Weekly News, January 22 to 28, 2024
Automates New Radioligand Therapy Production Plant Novartis’ Lutathera reduces disease progression risk
- 📰 GPCR Weekly News, January 15 to 21, 2024
transport by CCHCR1 via direct interaction Industry News Novartis Lutathera® significantly reduced risk
- 📰 GPCR Weekly News, June 17 to 23, 2024
a G-protein coupled receptor-related gene signature through bioinformatics analysis to construct a risk