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13 items found for "Autophagy"
- β-arrestin1 promotes tauopathy by transducing GPCR signaling, disrupting microtubules and autophagy
studies show that β-arrestin1 drives tauopathy by destabilizing microtubules and impeding p62/SQSTM1 autophagy
- HBx induces hepatocellular carcinogenesis through ARRB1-mediated autophagy to drive the G 1/S cycle
for complete autophagy. Inhibition of autophagy by 3-methyladenine or interference of ATG5 or ATG7 attenuated HBx-induced cell The absence of autophagy abolished the phosphorylation of CDK2 and the activity of the CDK2-CCNE1 complex Our results demonstrate that ARRB1 plays a critical role in HBV-related HCC via modulating autophagy related 5; ATG7: autophagy related 7; Baf A1: bafilomycin A1; CDK2: cyclin dependent kinase 2; CDKN1B
- Sweet taste receptor agonists attenuate macrophage IL‐1β expression and eosinophilic inflammation...
taste receptor agonists attenuate macrophage IL‐1β expression and eosinophilic inflammation linked to autophagy Autophagy deficiency in myeloid cells plays a causal role in eosinophilic CRS (ECRS) via macrophage IL ‐1β overproduction, thereby suggesting autophagy regulation as a potential therapeutic modality. Trehalose is a disaccharide sugar with known pro‐autophagy activity and effective in alleviating diverse We sought to investigate the therapeutic potential of autophagy‐enhancing agent, trehalose, or related
- GPCR Signaling and mTORC1 Regulation
mTOR) senses upstream stimuli to regulate numerous cellular functions such as metabolism, growth, and autophagy
- 📰 GPCR Weekly News, March 18 to 24, 2024
Receptor Deciphering the role of glycosaminoglycans in GPCR signaling G protein-coupled receptor-mediated autophagy
- 📰 GPCR Weekly News, June 3 to June 9, 2024
identification of a G protein-biased allosteric modulator of cannabinoid receptor CB1 GPCR function in autophagy
- 📰 GPCR Weekly News, February 26 to March 3, 2024
circuits GPCRs in Oncology and Immunology RGS20 promotes non-small cell lung carcinoma proliferation via autophagy
- 📰 GPCR Weekly News, June 26 to July 2, 2023
High expression of GPR50 promotes the proliferation, migration and autophagy of hepatocellular carcinoma
- 📰 GPCR Weekly News, November 13 to 19, 2023
and Signaling Butyrate induces STAT3/HIF-1α/IL-22 signaling via GPCR and HDAC3 inhibition to activate autophagy
- 📰 GPCR Weekly News, December 18 to 31, 2023
astrocytes for Parkinson's disease therapy: unraveling the Foxg1-mediated neuroprotective mechanism through autophagy-mediated
- 📰 GPCR Weekly News, January 29 to February 4, 2024
β-arrestins and its potential role in heart failure GPCRs in Neuroscience Role of lipids in the control of autophagy
- 📰 GPCR Weekly News, March 27 to April 4, 2023
The adhesion G-protein-coupled receptor VLGR1/ADGRV1 controls autophagy.
- 📰 GPCR Weekly News, March 6 to 12, 2023
and Immunology GPR176 Promotes Cancer Progression by Interacting with G Protein GNAS to Restrain Cell Mitophagy