News < GPCRs in Oncology and Immunology RGS20 promotes non-small cell lung carcinoma proliferation via autophagy Western blotting demonstrated different expressions of autophagy and the Hippo-PKA signal pathway. Further, RGS20 accelerated cell proliferation by increasing autophagy. Remarkably, inhibiting Hippo signaling with GA-017 promoted cell proliferation and activated autophagy Conclusion: Our findings indicate that RGS20 drives NSCLC cell proliferation by triggering autophagy

GPCRs in Oncology and Immunology High expression of GPR50 promotes the proliferation, migration and autophagy transfected into HCC cell line CBRH-7919, and we found that Gpr50 promoted the proliferation, migration, and autophagy together, GPR50 may promote HCC progression via CCT6A-induced proliferation and PGK1-induced migration and autophagy

cellular protein that has turned out to be very relevant in the control of the cellular process known as autophagy been published in the journal Nature Communications (12 (1):4540, 2021) with the title "Gαq controls autophagy

and Immunology GPR176 Promotes Cancer Progression by Interacting with G Protein GNAS to Restrain Cell Mitophagy GPR176 is confirmed to activate the cAMP/PKA signaling pathway and modulate mitophagy, promoting CRC The GPR176/GNAS complex inhibits mitophagy via the cAMP/PKA/BNIP3L axis, thereby promoting the tumorigenesis Tuo Wang , Peng Yang , Ji'ou Gu , Yifei Feng , Kangpeng Jin , Xiaowei Wang , Yueming Sun Tags GPCR , autophagy

where I started working on membranes and membrane protein biochemistry by studying membrane fusion and autophagy