Each of these receptors activates G protein-coupled inwardly rectifying potassium (GIRK) channels. have shown that co-activation using saturating concentrations of agonists results in occlusion of the GIRK The results indicate that a low tonic level of G βγ results in facilitation of GIRK current and a high The results suggest that the cooperative interaction between G βγ subunits and GIRK channels determines Activation of either D2 or GABAB receptors also acutely desensitized the GIRK channel current induced

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McGill along the dopamine circuit Date & Time Friday, November 3rd / 8:55 AM Abstract Coming Soon About Bruno Giros "Bruno Giros' lab is dedicated to investigating how molecular changes at the nerve synapse might Giros created the INSERM/CNRS laboratory on the "Neurobiology of Psychiatric Disorders", at the University Brunos Giros on the web The Douglas Research Centre McGill University Pubmed Google Scholar LinkedIn

Institute Read More Friday, November 3rd / 8:55 AM A journey from Duke to McGill along the dopamine circuit Bruno Giros McGill University Read More Friday, November 3rd / 9:20 AM Cannabinoid compounds to augment L-DOPA

Authors Karthik Nath, Tala Shekarkhand, David Nemirovsky, Andriy Derkach, Bruno Almeida Costa, Noriko