September 2022 Exploiting Dependence of Castration-Resistant Prostate Cancer on the Arginine Vasopressin Signaling Axis by Repurposing Vaptans "Men with advanced prostate cancer are treated by androgen deprivation therapy but the disease recurs as incurable castration-resistant prostate cancer (CRPC), requiring new Interrogation of prostate cancer patient sample data revealed that coexpression of AVPR1A and AVPR2 is

), the therapeutic benefits of the β-adrenergic receptor antagonist, propranolol, were described in benign

more Elucidation of active components and target mechanism in Jinqiancao granules for the treatment of prostatitis and benign prostatic hyperplasia GPCRs in Cardiology, Endocrinology, and Taste Blockade of endothelial

and benign prostatic hyperplasia Published date June 28, 2024 Abstract " Ethnopharmacological relevance : Prostatitis and benign prostatic hyperplasia (BPH) are inflammations of the prostate gland, which surrounds Aim of the study: We hypothesized that Jinqiancao granules could be a potential therapy for prostatitis Liangliang Zhou, Wenjie Yuan, Wanxian Wang, Yumin Yao, Jixia Wang, Yanfang Liu, Xinmiao Liang Tags Benign prostatic hyperplasia , G-protein coupled receptor , Jinqiancao granules , Network pharmacology , Prostatitis

GPCR News < GPCRs in Oncology and Immunology Autocrine proteinase-activated receptor signaling in PC3 prostate PARs are highly expressed in many cancer cells, including prostate cancer (PCa), and regulate various In this study, we examined the androgen-independent human prostatic cancer cell line PC3 and find the

Clinical, pathophysiologic, genetic and therapeutic progress in Primary Bilateral Macronodular Adrenal Hyperplasia Published date December 22, 2022 Abstract Patients with primary bilateral macronodular adrenal hyperplasia (PBMAH) usually present bilateral benign adrenocortical macronodules at imaging and variable levels Fanny Chasseloup , Peter Kamenicky , André Lacroix Tags ARMC5 , KDM1A , Cushing’s syndrome , adrenal hyperplasia