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7 items found for "Bongers BJ"
- TM5-TM6: structural switches that modulate the coupling of serotonin receptors to Gs or Gi
evidenced that 5-HT4/6/7-Gs coupled receptors have a cytosolic TM5 that is on average 5.7 residues longer regions of 27 class A GPCRs coupled to Gs or Gi/o yielded similar results, TM5 was 5.6 ± 1.5 residues longer
- G protein-coupled receptors that influence lifespan of human and animal models
Humanity has always sought to live longer and for this, multiple strategies have been tried with varying
- Discover the Hottest GPCR News of the Week: Oct 7-13, 2024!
receptor signaling kinetics and concentration-dependent responses using ONE-GO biosensors Why wait any longer
- Harnessing Deep Mutational Scanning for Enhanced Drug Discovery
essential advancement will be the integration of DMS with emerging sequencing technologies that allow for longer
- Unlocking Cell's Secrets: Spontaneous β-Arrestin-Membrane Preassociation Drives Receptor-Activation
The above causes β-arrestin molecules to stay longer and accumulate on the plasma membrane, allowing
- Artificial intelligence – faster, smarter, cheaper GPCR drug discovery
For this reason, DL models generally require more computational resources (such as powerful GPUs) and longer
- Molecular basis for ligand modulation of the cannabinoid CB 1 receptor
ARTICLES: This article is part of a themed issue on Structure Guided Pharmacology of Membrane Proteins (BJP
