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68 items found for "Bryan L Roth"
- Ep 14 with Dr. Bryan Roth
Bryan Roth About this episode Dr. Bryan Roth is the Michael Hooker Distinguished Professor of Pharmacology at the University of North Carolina Join me and learn more about Bryan and his work. Dr. Bryan Roth on the web UNC School of Medicine / Pharmacology Roth Lab Roth Leads $26.9 Million Project to Create Better Psychiatric Medications LinkedIn Bryan Roth on Twitter Roth Lab on Twitter Google Scholar
- Cannabinoid compounds to augment L-DOPA treatment in Parkinson's Disease
Contest Committee Sponsors GPCR Retreat Program < Back to schedule Cannabinoid compounds to augment L-DOPA
- Ep 102 with Dr Caron Tribute Part 3
Bryan Roth (current) Dr. Ali Salahpour (2007) Dr. Lauren Sloksy (2020) Dr. Josh C Snyder (2012) Dr.
- [Inhibitory effect of downregulating G protein-coupled receptor class C group 5 member A expression on lipopolysaccharide-induced inflammatory response in human gingival fibroblasts]
GFs were isolated with enzymic digestion and transfected with 30, 50 and 80 μmol/L small interfering The 50 μmol/L group displayed the most significant decrease in GPRC5A expression (31.16±3.29) compared blotting analysis showed that siGPRC5A (0.27±0.03, 0.71±0.00) suppressed the expressions of GPRC5A at both The siGPRC5A+LPS group (0.39±0.03, 1.06±0.16) also inhibited the increase of GPRC5A at both gene and Authors Y H Hu , L L Shang , S H Ge Source Contribute to the GPCR News Coming soon Become a Contributor
- Dr. GPCR Summit 2021 Live Talks
Brian Arey, Dr. Samuel Hoare, Dr. Ajay Yekkirala, Dr. Bryan Roth September 17, 2021 at 7:00:00 PM Learn More >> Nanobody tethering to dissect GPCR pharmacology
- The GPCR-Gαs-PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure
Authors Victoria H Wu , Bryan S Yung , Farhoud Faraji , Robert Saddawi-Konefka , Zhiyong Wang , Alexander
- Spliceosome mutations are associated with clinical response in a phase 1b/2 study of the PLK1 inhibitor onvansertib in combination with decitabine in relapsed or refractory acute myeloid leukemia
Authors Peter J P Croucher , Maya Ridinger , Pamela S Becker , Tara L Lin , Sandra L Silberman , Eunice
- Ep 34 with Dr. Brian Arey
Brian Arey About this episode Brian Arey is Senior Director of Mechanistic Pharmacology within Leads He obtained both his MS and Ph.D. in Neuroendocrine Physiology at Florida State University before completing Brian has contributed to the discovery or development of 5 marketed drugs through his work spanning molecular I sat down with Brian to chat about GPCRs, working in the industry, and being a leader. Brian Arey on the web LinkedIn ResearchGate Pubmed Dr.
- Elucidation of active components and target mechanism in Jinqiancao granules for the treatment of prostatitis and benign prostatic hyperplasia
., Pyrrosia calvata (Baker) Ching, Plantago asiatica L. and stigma of Zea mays L.
- Ep 105 with Annabelle Milner
In particular, she is looking at L- and D-lactate-activated HCAR1 signaling.
- G protein-coupled estrogen receptor (GPER)/GPR30 forms a complex with the β1-adrenergic receptor, a membrane-associated guanylate kinase (MAGUK) scaffold protein, and protein kinase A anchoring protein (AKAP) 5 in MCF7 breast cancer cells
Both receptors contain PSD-95/Discs-large/ZO-1 homology (PDZ) motifs in their C-terminal tails through Authors Julia Tutzauer , D Stephen Serafin , Tobias Schmidt , Björn Olde , Kathleen M Caron , L M Fredrik
- Dopamine-Mediated Motor Recovery after Ischemic Stroke
hope our research will aid in the development of new therapeutic interventions for the alleviation of L-DOPA-induced
- Ep 40 with Dr. Brian Bender
Brian Bender About Dr. Brian Bender Dr. Between undergraduate and graduate school Brian worked as a technician in an academic lab before moving Brian is involved in organizing the GRC/GRS Molecular Pharmacology meeting, which has been postponed Brian is one of the organizers of the upcoming Transatlantic ECI GPCR Symposium . Dr. Brian Bender on the web LinkedIn Twitter ResearchGate Dr.GPCR Member Google Scholar Dr.
- Ep 94 with Dr. Brian Shoichet
GPCR Podcast << Back to podcast list Brian Shoichet About Dr. Brian Shoichet BSc in Chemistry from MIT, Ph.D. with Tack Kuntz at UCSF; Postdoc with Brian Matthews Brian Shoichet on the web Google Scholar Shoichet Lab Twitter Dr.
- Ep 103 with Dr Kathleen Caron
Caron, Ph.D. is the Frederik L.
- "Have a nice weekend, and I'll see you tomorrow!": RAMP-interacting GPCR Pathways
Caron, Ph.D. is the Frederik L.
- CaaX-motif-adjacent residues influence G protein gamma (Gγ) prenylation under suboptimal conditions
Authors Mithila Tennakoon , Waruna Thotamune , John L Payton , Ajith Karunarathne Tags HMG-CoA reductase
- Wnt pathway inhibition with the porcupine inhibitor LGK974 decreases trabecular bone but not fibrosis in a murine model with fibrotic bone
Authors Hsuan Lung, Kelly L Wentworth, Tania Moody, Ariane Zamarioli, Apsara Ram, Gauri Ganesh, Misun
- Ep 137 with Dr. Josh Pottel
Brian Shoichet at UCSF. More broadly, I hope to be a critical contributor to a growing Canadian biotech sector in both scientific
- Session I
available for AGPCR 24 Workshop Attendees Authors & Affiliations "Rosell, Júlia (1) Holmkvist, Jesper L. In our previous work, we reported the structures of a prototypical aGPCR CD97 in both inactive and active we have elucidated the high-resolution structures of GPR97 transitioning from its inactive state to both Bernadyn, Mariane Nascimento, Xinyi Lu, Pauline L. Pan, Michael Holinstat and Gregory G.
- Ep 145 with Dr John Janetzko
Brian Kobilka at Stanford University at the end of 2017 for postdoctoral work. He chose Brian's lab due to his interest in studying conformational changes. John shared his experience of reaching out to and securing a position in Brian's lab. Both agreed on the importance of adaptability, as unexpected situations like the Covid-19 pandemic can The conversation concluded with both John and Yamina expressing a desire to support the academic community
- Ep 70 with Dr. Stephen Ferguson
Brian Collier in the Department of Pharmacology and Therapeutics at McGill University (1994). He has also received both Junior (2001) and Senior (2005) investigator awards from the Pharmacological
- CCR7 acts as both a sensor and a sink for CCL19 to coordinate collective leukocyte migration
< GPCR News < GPCRs in Oncology and Immunology CCR7 acts as both a sensor and a sink for CCL19 to coordinate Such a dual role of CCR7 as a GPCR that both senses and consumes its ligand can thus provide a novel
- Ep 69 with Dr. Stephen Ferguson
Brian Collier in the Department of Pharmacology and Therapeutics at McGill University (1994). He has also received both Junior (2001) and Senior (2005) investigator awards from the Pharmacological
- Ep 129 with Dr. Kaavya Krishna Kumar
Brian Kobilka's lab at Stanford University, USA.
- GPCR Retreat 2023 - Part I
Caron, Ph.D. is the Frederik L.
- Ep 58 with Dr. Juan José Fung
Brian Kobilka , studying the dimerization of GPCRs. Dr.
- Ep 15 with Dr. Arun Shukla
Brian Kolbika of Stanford University. Join us and learn more about Dr.