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147 items found for "CP: Metabolism"

Posts (103)

  • The regulation of PKA signaling in obesity and in the maintenance of metabolic health

    synaptic events, exocytosis, transcriptional regulation, and more, PKA signaling regulates cellular metabolism afferent and peripheral efferent signals that link specific neural cell populations to the regulation of metabolic Mouse models have provided invaluable information on the roles for PKA subunits in brain and key metabolic Variants identified in PKA subunit genes cause Cushing syndrome that is characterized by metabolic dysregulation

  • Protein Uncoupling as an Innovative Practice in Diabetes Mellitus Treatment: A Metabolic Disorder

    October 2022 "Background: Uncoupling proteins (UCPs) are unpaired electron carriers that uncouple oxygen intake by the electron transport chain from ATP production in the inner membrane of the mitochondria. The physiological activities of UCPs have been hotly contested, and the involvement of UCPs in the pathogenesis and progression of diabetes mellitus is among the greatest concerns. UCPs are hypothesised to be triggered by superoxide and then reduce mitochondrial free radical production, potentially protecting diabetes mellitus patients who are experiencing oxidative stress. Objectives: The objectives of the study are to find out the newest ways to treat diabetes mellitus through protein uncoupling." Read more at the source #DrGPCR #GPCR #IndustryNews

  • Inversago Pharma Announces Dosing of First Participant with Metabolic Syndrome in Phase 1B ...

    March 2022 Inversago Pharma Announces Dosing of First Participant with Metabolic Syndrome in Phase 1B unique portfolio of CB1 inverse agonists, announced today the dosing of the first participant with metabolic pharmacokinetics and safety profile of Inversago’s lead molecule, INV-202, on a targeted population with metabolic

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