Kazemi, Xin Li, Amitis Akbari, Kei Sakano, Yoshihiro Sakano, Benjamin P Hurrell, Omid Akbari Tags CB2 , CP : Immunology , CP: Metabolism , ILC2 , T2DM , adipose inflammation , glucose tolerance , immunotherapy

Bhagat , Aarushi Singhal , Shani Austin-Williams , Shantanu Sengupta , Manikandan Subramanian Tags CP

GPCR Podcast << Back to podcast list Re-cap of Endocrine Metabolic GPCR 2024 with the Organizers About Aylin Hanyaloglu on the web LinkedIn Endocrine Metabolic GPCRs Researchgate Twitter Imperial College Her current research focuses on how metabolic GPCRs cross-talk and interact to regulate appetite and bone metabolism." Caroline Gorvin on the web University of Birmingham Endocrine Metabolic GPCRs Society of Endocrinology

Oncology and Immunology GPR37 promotes colorectal cancer against ferroptosis by reprogramming lipid metabolism GPR37 protects cancer cells from ferroptosis by upregulating SCD1 expression, thereby modulating lipid metabolism Mechanistic studies have shown that GPR37 modulates lipid metabolism in tumor cells by promoting SCD1 Li, Zhen Xiang, Yixiu Wang, Ti Zhang, Weiqi Xu, Lu Wang, Anrong Mao Tags Ferroptosis , GPR37 , Lipid metabolism

Pharmacological and Genetic Preclinical Models of Ghrelin Receptor Functional Selectivity to Investigate Metabolic in exploiting GPCR biased signaling to design/develop new pharmacotherapeutics to treat reward- and metabolism-based is to better understand the underlying mechanisms of food reward and its downstream dysregulation of metabolic develop novel GPCR pharmacotherapies that improve efficacy and minimize side effects for diet-induced metabolic

inflammation and defense Published date March 5, 2024 Abstract "Immune cells undergo rapid and extensive metabolic In addition to contributing to energetic and biosynthetic demands, metabolites can also function as signaling This metabolite binds to and regulates the function of diverse proteins intracellularly to influence metabolism, oxidative response, epigenetic modification, and gene expression and to signal extracellularly In this article, we review ITA metabolism and its regulation, discuss its target proteins and mechanisms

is to develop GPCR-based drugs for the treatment of obesity and Type 2 Diabetes (T2D) by exploring metabolically immune cell GPCRs and their cross-talk with other insulin-sensitive tissues regulating glucose and lipid metabolism Sai Prasad Pydi on the web Molecular Metabolism & Cell Signaling Laboratory Website Twitter.com Research

Calebiro is Chair of Molecular Endocrinology and Wellcome Trust Senior Research Fellow at the Institute of Metabolism Stockholm, and obtained a PhD in Molecular Medicine and a Clinical Specialisation in Endocrinology and Metabolic basic mechanisms of G protein-coupled receptor (GPCR) signalling and their alterations in endocrine, metabolic

< GPCR News < GPCRs in Oncology and Immunology Metabolic crosstalk: Extracellular ATP and the tumor microenvironment This review explores e-ATP metabolism, its purinergic signaling, and therapeutic strategies targeting

studying structural and mechanistic properties of ghrelin receptor and GPCRs involved in regulation of metabolism After completing his Ph.D., he pursued research in genetics of metabolic regulation at the Institute of Metabolic Science - Metabolic Research Laboratories at the University of Cambridge in the team led series of novel human genetic variants identified in several GPCRs associated with obesity and other metabolic

Laporte is a Professor of Medicine, and the Director of Research of the Division of Endocrinology and Metabolism He is also an Associate Leader of the Experimental Therapeutics and Metabolism Program and the Director

Nordström (Umeå, Sweden), I broadened my methodical and scientific horizon and focused on cellular metabolism Our ultimate goal is to understand their role in immune cell function and cancer cell metabolism. " Dr Yamina expressed interest in attending a meeting about GPCRs and metabolism in the UK, but was unsure Metabolite Activation of GPCRs: A Fascinating Discovery Claudia and Yamina discussed the role of metabolites example she heard in a podcast about fecal transplants and the relationship between the gut, brain, and metabolism

complex with β-arrestin-1 and CFTR at apical membrane of efferent ductulus to regulate the salt/water metabolism unsaturated fatty acids) and other lipids by GPCRs (Science 2023, Science Advance 2021, PNAS 2023, Nature Metabolism

Furthermore, GprC and AcyA regulate the primary metabolism as well as secondary metabolism, and further

Functional annotation of GPR37 showed enrichment of ether lipid metabolism, fat digestion and absorption , and histidine metabolism.

laboratory is focused on the molecular mechanisms of aging, with an emphasis on stress response and metabolism

placement at the Charles Perkins Centre in Sydney, investigating the effects of dietary carbohydrates on metabolic Annabelle’s Ph.D. work focuses on microbial-derived metabolites that signal through GPCRs expressed in

Milligan is the co-founder of both Caldan Therapeutics (2015) which discovers novel therapeutics for metabolic

Prior to Crinetics, he was senior director and head of endocrinology and metabolism at Neurocrine Biosciences

healthy controls and tested associations of serum autoantibody levels with serological, haemodynamic, metabolic However, they are correlated poorly or even inversely to haemodynamic, metabolic, and functional markers

abstract category on top left corner (up to 2 categories max) Abstract categories Signaling Trafficking Metabolism

record in exploring GPCR structure-function relationships in the context of cardiovascular disease and metabolic

subsequent postdoctoral work that led to Nick's interest in peptide messengers regulating appetite, metabolism

discovery targeting GPCR ( Confo Therapeutics ) as a team and project leader for antibody discovery for metabolic

Our recent study revealed that a protein complex consisting of copper metabolism MURR1 domain-containing

adenosine signaling and discuss unexpected links between the adenosinergic pathway, DNA damage response and metabolic

Published date June 14, 2024 Abstract "Initiation of development requires differential gene expression and metabolic

G protein-coupled receptors (GPCRs) are involved in endocrine and metabolic processes as well as many