Previous findings suggest that parallel pathways independently relay innate threat signals from different Here, we report that neurons expressing calcitonin gene-related peptide (CGRP) in the parvocellular subparafascicular parabrachial nucleus in the brainstem respond to multi-sensory threat cues from various sensory modalities and relay innate threat pathways may provide insights into developing therapeutic candidates for innate fear-related

Vries, Graham Ladds, Antoinette MaassenVanDenBrink, et al. for their work on Intracellular pathways of calcitonin gene-related peptide-induced relaxation of human coronary arteries: A key role for Gβγ subunit instead Melanin-concentrating hormone receptor 1 is discarded by exosomes after internalization Intracellular pathways of calcitonin gene-related peptide-induced relaxation of human coronary arteries: A key role for Gβγ subunit instead dynamics using single-molecule fluorescence Droplet-based microfluidic platform for detecting agonistic peptides

receptor Revealing the graded activation mechanism of neurotensin receptor 1 Intracellular pathways of calcitonin gene-related peptide-induced relaxation of human coronary arteries: A key role for Gβγ subunit instead neuroactive signals and may onset metabolic disturbances GPCR Binders, Drugs, and more Gut microbe-generated Alzheimer's disease Nanoplastic at environmentally relevant concentrations induces toxicity across multiple generations Mapping GPCR-RAMP complexes with MolBoolean Screening GPR75 Modulators Using Medium-Throughput Reporter Gene

Antibody-dependent cellular cytotoxicity , Atopic dermatitis , BAM8-22 , BP , Beta chain , Bovine adrenal medulla peptide pemphigoid , C-C motif chemokine ligand 17 , CCL17 , CGRP , CIU , COPD , CRSsNP , CRSwNP , CSF2 , CSU , Calcitonin gene-related peptide , Chronic idiopathic urticaria , Chronic obstructive pulmonary disease , Chronic family of G protein-coupled receptor 11 , Mas-related family of G protein-coupled receptor X1 , Mas-related Transient receptor potential vanilloid 1 , US Food and Drug Administration , VIP , Vasoactive intestinal peptide

< GPCR News < GPCRs in Oncology and Immunology Identification of a G-protein coupled receptor-related gene signature through bioinformatics analysis to construct a risk model for ovarian cancer prognosis We aimed to identify GPCR-related gene (GPCRRG) signatures and develop a novel model to predict OV prognosis Method: We downloaded data from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases The immunological characteristics of the high- and low-risk groups were analyzed using single-sample gene

GBP1 expression through GPCR receptor Mthl10 Published date January 29, 2024 Abstract "Growth-blocking peptide A functional analogue of GBP, stress-responsive peptide (SRP), was also identified in the same species SRP gene expression has been also demonstrated to be enhanced by GBP, indicating that both cytokines It is expected that the biological responses of two structurally similar peptides should be coordinated GBP2 system can be a simple model that is useful to investigate the detailed regulatory mechanism of related