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54 items found for "Can Cao"
- Regulator of G protein signaling 16 restrains apoptosis in colorectal cancer through disrupting TRAF6-TAB2-TAK1-JNK/p38 MAPK signaling
Jie Yuan, Dafeng Tong, Bingchen Chen, Enda Yu, Guanglei Chen, Cheng Peng, Wenjun Chang, Jifu E, Fuao Cao
- GPCR Courses
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- Dr. GPCR Summit 2021 | Dr. GPCR Ecosystem
How can I sponsor the 2021 Summit? For more information, please email us at Hello@DrGPCR.com In what form can I submit my abstract? Pros: You can polish your recording to your satisfaction. Anyone can watch it from anywhere, even multiple times. Can I present a live talk or event? How?
- Ep 18 with Dr. Yamina Berchiche
The explosion of biomedical data such as in genomics, structural biology, and pharmacology can provide ML/AI can be powerful for identifying abstract patterns within large data where traditional methods would This comes without the need for manual feature engineering as systems can learn through implicit rules How can we best leverage these exciting new techniques in areas such as protein structure prediction,
- Interplay between G protein-coupled receptors and nanotechnology
Nanotechnology, as versatile techniques, can encapsulate GPCR ligands to assemble synthetic nano-GPCRs Moreover, endosomal delivery of GPCR ligands by nanoparticles can precisely initiate sustained endosomal In turn, due to overexpression of GPCRs on the surface of various types of cells, GPCR ligands can endow construct synthetic nano-GPCRs or detect GPCRs, while endosomal delivery of GPCR ligands by nanoparticles can Meanwhile, molecular engineering of nanoparticles with GPCRs or their ligands can modulate membrane binding
- Dr. GPCR Summit 2022 | Dr. GPCR Ecosystem
You can join us for free when you become a Dr. GPCR Ecosystem site member, which is also free! You can participate: As an attendee by becoming a site member. You can verify it too by checking out the schedule on our website. before September 30th, 2022 You'll need a 1-minute video abstract in addition to the written version You can
- Explore / Individuals | Dr. GPCR Ecosystem
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- Booklet for participants | Dr. GPCR Ecosystem
OFFICIAL BOOKLET Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF You can
- Atypical Structure and Function of Typical Chemokine Receptors
Although symptoms of GRIN disorder appear very early in childhood, it can take years to reach the right Many children experience seizures that can be life-threatening. These mice can then be used to test dietary regimens, drugs, and adenoviral gene therapies for their
- Ep 63 with Dr. Khaled Abdelrahman
Ottawa as a Postdoctoral Fellow to explore novel G protein-coupled receptor (GPCR) candidates that can been also studying what aspects of GPCR signaling are regulated in a sex-selective manner and how this can
- Role and recent progress of P2Y12 receptor in cancer development
P2Y12R activation can promote platelet aggregation and adhesion to cancer cells, promote tumor angiogenesis Meanwhile, P2Y12R inhibitors can inhibit this effect, suggesting that P2Y12R may be a potential therapeutic
- A positive Allosteric Modulator of M1 Acetylcholine Receptors Improves Cognitive Deficits in Male and Female Alzheimer’s Mice
Ottawa as a Postdoctoral Fellow to explore novel G protein-coupled receptor (GPCR) candidates that can been also studying what aspects of GPCR signaling are regulated in a sex-selective manner and how this can
- Small-molecule targeting of GPCR-independent noncanonical G-protein signaling in cancer
However, it has become evident that heterotrimeric G-proteins can also be activated via GPCR-independent By revealing that small molecules can selectively disable noncanonical mechanisms of G-protein activation
- Ep 113 with Dr. Prasenjit Saha
Science, Bangalore, India, to investigate the mechanisms behind rare mitochondrial diseases, which can potential diagnostic marker for CVD as it causes serious fatal conditions such as thrombus formation, which can
- Ep 71 with Dr. Jean Martin Beaulieu
regulated by dopamine receptors, thus providing a framework to understand how different drug classes can The Beaulieu group is presently investigating how cell surface express proteins can act as allosteric
- NPFF stimulates human ovarian cancer cell invasion by upregulating MMP-9 via ERK1/2 signaling
The pathogenesis of EOC can be regulated by many local factors, including neuropeptides, through an autocrine The TaqMan probe-based RT-qPCR showed that NPFF and NPFFR2 were expressed in three human EOC cells, CaOV3 In comparison, NPFF and NPFFR2 expression levels were higher in SKOV3 cells than in CaOV3 or OVCAR3 cells
- Combinatorial depletions of G-protein coupled receptor kinases in immune cells identify pleiotropic and cell type-specific functions
They can be recruited to agonist-activated G-protein coupled receptors (GPCRs) and phosphorylate their However, there is growing evidence that GRKs can also control cellular functions beyond GPCR regulation
- Ep 82 with Dr. Lauren M. Slosky
neuropeptide G protein-coupled receptors (GPCRs) regulate motivated behavior and how these receptors can is now working to understand how the principles of receptor allosterism and functional selectivity can
- GPCR Retreat 2023 - Part II
Ottawa as a Postdoctoral Fellow to explore novel G protein-coupled receptor (GPCR) candidates that can been also studying what aspects of GPCR signaling are regulated in a sex-selective manner and how this can
- Ep 12 with Dr. Antonella Di Pizio
Join us to learn more about chemosensory GPCRs and how computational pharmacology can help better understand
- University | Dr. GPCR Ecosystem
Contact us and find out how we can collaborate together.
- Ep 11 with Genemode
Today, Genemod has built a freezer management tool and a project management tool where scientists can
- Ep 25 with Dr. Annette Gilchrist
Join me and learn more about Annette’s career, our common love for chemokines, and how you can use your
- Trademark Policy | Dr. GPCR Ecosystem
GPCR users can connect to and share on Dr. GPCR. These include: - Dr. GPCR Share dialog and can be implemented using a Dr. GPCR icon. You can use these assets on your app (website or mobile app) without pre-approval provided you follow GPCR or to link to your Page so that users can follow you. You can do this so long as the context makes it clear what action will be taken when the user clicks
- Session IX / Technology capsule: Light on aGPCR signaling and function | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Novoprotein developed a NovoiSMART technology, utilizing mRNA-based immunization, which can overcome
- C-Principles1 (List) | Dr. GPCR Ecosystem
registrants will receive a comprehensive understanding of the unique science of pharmacology and how it can
- Ep 126 with Dr. Françoise Bachelerie
In particular, FB contributed to the discovery that CXCL12 is the ligand for the CXCR4 receptor and can