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Get ready to stay up-to-date with the latest research, advancements, and news in the field. From the scientist’s view: a conversation with … Chris Tate AI is dreaming up drugs that no one has ever

☕ We are excited to announce our rescheduled Dr. GPCR Virtual Cafe session with Dr. Matthew E. on Friday, October 7th at 1 PM ET. Don't miss the chance to listen to his latest research on the field. It's a great opportunity to get warmed up for the upcoming Summit starting the next Monday. Get your ticket today on Eventbrite! ➡https://bit.ly/3CmntVn

September 2022 "Perception of threats is essential for survival. Previous findings suggest that parallel pathways independently relay innate threat signals from different sensory modalities to multiple brain areas, such as the midbrain and hypothalamus, for immediate avoidance. Yet little is known about whether and how multi-sensory innate threat cues are integrated and conveyed from each sensory modality to the amygdala, a critical brain area for threat perception and learning. Here, we report that neurons expressing calcitonin gene-related peptide (CGRP) in the parvocellular subparafascicular nucleus in the thalamus and external lateral parabrachial nucleus in the brainstem respond to multi-sensory threat cues from various sensory modalities and relay negative valence to the lateral and central amygdala, respectively. Both CGRP populations and their amygdala projections are required for multi-sensory threat perception and aversive memory formation. The identification of unified innate threat pathways may provide insights into developing therapeutic candidates for innate fear-related disorders." Read more at the source #DrGPCR #GPCR #IndustryNews

Chris Tate About this episode Dr. Chris Tate obtained his Ph.D. from the University of Bristol in 1989 and then moved to the University Chris also worked on the E. coli multidrug transporter EmrE and obtained both 2D and 3D crystals as well Join me to learn more about Chris’s work and his role in founding Heptares which was later acquired by Chris Tate on the web LinkedIn ResearchGate Pubmed Google Scholar Sosei Heptares Wikipedia MRC Laboratory

Chris Tate and Dr. Richard Henderson at the Laboratory of Molecular Biology in Cambridge, UK. help us understand your needs to bring you exciting and informative content; this short survey should take

GPCR Podcast << Back to podcast list Chris Langmead Chris Langmead is Professor, Deputy Director, and in drug discovery, particularly in the field of psychiatry, where he has led multiple projects into late Prior to joining Heptares, Chris was a neuroscience researcher at GlaxoSmithKline, UK (1998-2009). Chris serves on the editorial boards of the British Journal of Pharmacology, ACS Chemical Neuroscience help us understand your needs to bring you exciting and informative content; this short survey should take