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Dimerization: Unveiling Its Role in Receptor Function and Signaling Sonja Peter , Brian Bender , Chris De Graaf   for their excellent work on Comparative Study of Allosteric GPCR Binding Sites and Their

April 2022 Ono Enters into Collaboration Agreement with Domain Therapeutics and Université de Montréal (Strasbourg, France; CEO: Pascal Neuville; “Domain”) and Université de Montréal (Québec, Canada; “UdM

This week's highlight includes congrats to Omolade Otun, Chris de Graaf, Cherine Bechara, et al. for

Tim De Groof! It’s not often when you get the best of both worlds - nano-bodies and #GPCRs.

the Department of Biochemistry and Molecular Medicine of the Faculty of Medicine of the Université de

Chris Cargill appointed as President and Chief Executive Officer • Dr.

De novo drug design: AI algorithms can generate new molecules with desired properties, such as binding chemical space, limiting their ability to identify truly novel chemotypes”(Thomas, Smith, O’Boyle, de Graaf & Bender, 2021) and 4) limit of input data can lead to a phenomenon called “the burden of sequence

success Sosei and PharmEnable extend neurological disease drugs hunt Sosei Heptares’ President & CEO Chris

INV-202, an Oral, Peripherally-acting CB1 Inverse Agonist, in Patients with Diabetic Kidney Disease Chris

Member Profile Antony Boucard Professor Centro de Investigación y de Estudios Avanzados del IPN (Cinvestav AB: Favorite Taco: Taco de suadero (pronounced swa-day-ro), fatty, with meat caramelized in its own fat

Topline Safety and Tolerability Data from Proof-of-Concept Studies Sosei Heptares’ President & CEO Chris

From the scientist’s view: a conversation with … Chris Tate AI is dreaming up drugs that no one has ever

Graaf, C., et al., Glucagon-Like Peptide-1 and Its Class B G Protein-Coupled Receptors: A Long March

  Madelyn N Moore , Kelsey L Person , Abigail Alwin , Campbell Krusemark , Ezequiel Marron Fernandez de loss after a year, with no plateau INAUGURATION OF AELIS FARMA NEW LABORATORY at Institut Européen de

Domain Therapeutics was nominated for the Trophée de l'Innovation Technologique (Technological Innovation

Therefore, matching a ligand to an orphan GPCRs, the process of de-orphanizing, is of great importance

Michel Bouvier received the title of Doctor Honoris Causa from the Université de Montpellier Domain Therapeutics

GPCR drugmaker Septerna amasses $288M in IPO Surrounded by AI bio giants, tiny startup Nabla Bio makes de

This week's highlight includes congrats to: Tessa de Vries, Graham Ladds, Antoinette MaassenVanDenBrink

ended 31 December 2022 Addex Raises $5.0 Million in Equity Financing Testing the limits of SMILES-based de

., Rodríguez De Fonseca, F., Puente, N., Marsicano, G., & Grandes, P. (2016).

Cary, B.P., et al., New Insights into the Structure and Function of Class B1 GPCRs.  

., Choi, H. J., Fung, J. J., Pardon, E., Casarosa, P., Chae, P. S., Devree, B. T., Rosenbaum, D.