Search Results
64 items found for "Chun-Chun Chang"
- Olfactory Receptors and Tumorigenesis: Implications for Diagnosis and Targeted Therapy
Authors Yi Tang, Ye Tian, Chun-Xia Zhang, Guo-Tai Wang Tags G Protein-coupled receptors , Olfactory receptors
- Small-molecule targeting of GPCR-independent noncanonical G-protein signaling in cancer
, Vincent DiGiacomo , Mariola Ferreras-Gutierrez , Shiva Dastjerdi , Alain Ibáñez de Opakua , Jong-Chan Park , Alex Luebbers , Qingyan Chen , Aaron Beeler , Francisco J Blanco , Mikel Garcia-Marcos .
- TIPE proteins control directed migration of human T cells by directing GPCR and lipid second messenger signaling
C terminal amino acids, and that TIPE2 protein interacted with PIP2 and PIP3 through its positively charged Authors Jiyeon Yu , Ali Zamani , Jason R Goldsmith , Zienab Etwebi , Chin Nien Lee , Youhai H Chen ,
- Regulator of G protein signaling 16 restrains apoptosis in colorectal cancer through disrupting TRAF6-TAB2-TAK1-JNK/p38 MAPK signaling
Authors Hao Shen, Jie Yuan, Dafeng Tong, Bingchen Chen, Enda Yu, Guanglei Chen, Cheng Peng, Wenjun Chang
- Itaconate in host inflammation and defense
and defense Published date March 5, 2024 Abstract "Immune cells undergo rapid and extensive metabolic changes Authors Dan Ye , Pu Wang , Lei-Lei Chen , Kun-Liang Guan , Yue Xiong Tags IRG1/ACOD1 , cancer , inflammatory
- GPCR signaling contributes to immune characteristics of microenvironment and process of EBV-induced lymphomagenesis
Authors Jie Xiong , Yu-Ting Dai , Wen-Fang Wang , Hao Zhang , Chao-Fu Wang , Tong Yin , Shu Cheng , Hui-Juan Zhong , Shan-He Yu , Lu Jiang , Sheng-Yue Wang , Hai Fang , Rui-Hong Zhang , Yue Zhu , Hong-Mei Yi , Xu-Feng Jiang , Jia-Yi Chen , Li Wang , Peng-Peng Xu , Sai-Juan Chen , Wei-Li Zhao Tags CCR1 , Epstein-Barr
- PAXIP1-AS1 is associated with immune infiltration and predicts poor prognosis in ovarian cancer
Authors Buze Chen , Xiaoyuan Lu , Qingmei Zhou , Qing Chen , Siyan Zhu , Guilin Li , Hui Liu Source Contribute
- Exploiting frequent and specific expression of PRL3 in pediatric solid tumors for first-in-child use of PRL3-zumab humanized antibody
Abhishek Gupta , Sheng Hui Tan , Kelvin Kam Yew Kuan , Koon Hwee Ang , Khurshid Merchant , Kenneth Tou En Chang , Hui Yi Yon , Yong Chen , Mathew Hern Wang Cheng , Arjandas Mahadev , Matthew Chau Hsien Ng , Michaela
- Regulator of G protein signaling protein 6 alleviates acute lung injury by inhibiting inflammation and promoting cell self-renewal in mice
HE staining, ELISA, and immunohistochemistry were used to evaluate pathological changes and the degree vitro, qRT‒PCR, immunofluorescence staining, and western blotting were used to determine the dynamic changes Compared with the control group, we found higher mortality, more pronounced body weight changes, more Authors Juan Song , Miao Li , Cuicui Chen , Jian Zhou , Linlin Wang , Yu Yan , Jun She , Lin Tong , Yuanlin
- Targeting adenosine signaling for immuno-oncology
About John Stagg "John Stagg is a Professor of Pharmacy at Université de Montréal and researcher at the CHUM
- miR-19a may function as a biomarker of oral squamous cell carcinoma (OSCC) by regulating the signaling pathway of miR-19a/GRK6/GPCRs/PKC in a Chinese population
Authors Jijun Chen , Liang Wang , Danhua Ma , He Zhang , Jiayan Fan , Hongyan Gao , Xinyu Xia , Wei Wu
- Activation of orphan receptor GPR132 induces cell differentiation in acute myeloid leukemia
Authors Chunyang Yi, Jiacheng He, Dan Huang, Yumiao Zhao, Chan Zhang, Xiyun Ye, Ying Huang, Ruth Nussinov
- GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis
Park , Semin Lee , A Reum Je , Yang Hoon Huh , Sun-Young Kong , Taejoon Kwon , Pann-Ghill Suh , Young Chan
- Delivery of US28 by incoming HCMV particles rapidly attenuates Akt activity to suppress HCMV lytic replication in monocytes
Biswas, Michael J Miller, Julia E Myers, Stephen M Matthews, Amanda B Wass, Christine M O'Connor, Gary C Chan
- Ep 50 with Dr. Thomas P. Sakmar
the course included Marc Chabre , Harden McConnell , Richard Henderson , Martin Rodbell , Jean-Pierre Changeux Recently, Tom’s lab discovered, along with Yu Chen and Ping Chi , that a mutant of CYSLTR2 is a driver
- Comparison of infectious complications with BCMA-directed therapies in multiple myeloma
Nemirovsky, Andriy Derkach, Bruno Almeida Costa, Noriko Nishimura, Tasmin Farzana, Colin Rueda, David J Chung
- GPR37 expression as a prognostic marker in gliomas: a bioinformatics-based analysis
Authors Kairong Liang , Zhaoxiong Guo , Shizhen Zhang , Danmin Chen , Renheng Zou , Yuhao Weng , Chengxiang Peng , Zhichao Xu , Jingbai Zhang , Xiaorui Liu , Xiao Pang , Yunxiang Ji , Degui Liao , Miaoling Lai
- Exploration of prognostic and treatment markers in hepatocellular carcinoma via GPCR-related genes analysis
Authors Yuxin Wang , Bao Jin , Xiangan Wu , Jiali Xing , Baoluhe Zhang , Xiaokun Chen , Xiao Liu , Xueshuai
- GPCR Retreat Schedule 2023
Read More Friday, November 3rd / 4:35 PM Targeting adenosine signaling for immuno-oncology John Stagg CHUM
- Session V | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Authors & Affiliations "Chung, Yin Kwan2, Pohl, Fabian2, Batebi, Hossein1 Sträter, Norbert3 , Langenhan
- Stable Binding of Full-Length Chemerin is Driven by Negative Charges in the CMKLR1 N-terminus
News < GPCRs in Oncology and Immunology Stable Binding of Full-Length Chemerin is Driven by Negative Charges Here, we demonstrate that negative charges in the CMKLR1 N-terminus are involved in the formation of strong contacts with a specific positively charged patch at the surface of full-length chemerin, which
- Ep 107 with Dr. Roger Sunahara
structural work on the GPCR-G protein complexes have also revealed some unprecedented conformational changes Some of these changes are associated with G protein activation while the functional consequences of other structural changes remain elusive. have been heavily engaged in studies to address the functional role of these dramatic conformational changes
- Colorectal cancer incidence trends in Golestan, Iran: An age-period-cohort analysis 2004-2018
We calculated the estimated annual percentage change (EAPC) with 95 % confidence intervals (95 % CI) increasing trends in CRC incidence rates from 2004 to 2018 (EAPC = 3.7; 95%CI: 0.4, 7.1), with the greatest changes Conclusion: The increasing trends in CRC rates in Golestan are largely driven by generational changes
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- Esophageal and gastric cancer incidence trends in Golestan, Iran: An age-period-cohort analysis 2004 to 2018
The estimated annual percentage change (EAPC) with 95% confidence interval (95% CI) were calculated. The marked declines in EC incidence rates in Golestan relate to generational changes in its underlying
- Proteogenomic landscape and clinical characterization of GH-producing pituitary adenomas/somatotroph pituitary neuroendocrine tumors
ATP2A2 and ARID5B correlated with the GH change rate in the octreotide loading test, and WWC3, SERINC1 , and ZFAND3 correlated with the tumor volume change rate after somatostatin analog treatment.
- Unbiased multitissue transcriptomic analysis reveals complex neuroendocrine regulatory networks mediated by spinal cord injury-induced immunodeficiency
and objectives: The concentrations of adrenocorticotropic hormone and cortisol in plasma, as well as changes pathways related to inhibitory Gi-mediated G protein-coupled receptor (Gi-GPCR) neurons and neuropeptide changes genes: Ciart, per2, per3, cry1, and cry2) were enriched in cortisol secretion and circadian rhythm changes Authors Hong Zeng , Li Cheng , De-Zhi Lu , Shuai Fan , Ke-Xin Wang , Li-Li Xu , Bin Cai , Mou-Wang Zhou