This comprehensive course is designed to provide an in-depth exploration of key concepts in pharmacology , offering a nuanced understanding of drug interactions and mechanisms of action. The curriculum is divided into four modules, each focusing on essential aspects of pharmacological principles

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In this video, you'll be walked through the history and milestones of the Dr. GPCR Ecosystem.

August 2022 Dopamine D 1 receptor-mediated β-arrestin signaling: Insight from pharmacology, biology, of biased compounds as both research tools and novel drugs. Although this field has exploded during the past two decades, it is only recently that highly β-arrestin biased ligands for the dopamine D1 receptor were reported. Read more at the source #DrGPCR #GPCR #IndustryNews

Neuropeptides and their receptors have been documented in many hemipteran insects, but the differences precursors and 48 putative neuropeptide G protein-coupled receptor (GPCR) genes were identified in D. Additionally, we discovered that the neuropeptide signaling systems of Sternorrhyncha were very different research provides more knowledge on neuropeptide systems and sets the groundwork for the creation of novel D. Read more at the source #DrGPCR #GPCR #IndustryNews

October 2022 High hedgehog signaling is transduced by a multikinase-dependent switch controlling the apico-basal distribution of the GPCR smoothened "The oncogenic G-protein-coupled receptor (GPCR) Smoothened wing imaginal disc as a model. Together, these results link the morphogenetic effects of HH to the apico-basal distribution of SMO and Read more at the source #DrGPCR #GPCR #IndustryNews

Mice with constitutive Gαq/11 gene deletion exhibited abnormal alveolar development, with suppressed reduced TGFβ2 and elastin deposition. Cyclical mechanical stretch-induced TGFβ activation required Gαq/11 signalling and serine protease activity These data highlight a previously undescribed mechanism of cyclical stretch-induced Gαq/11-dependent Tags Alveologenesis , Cyclical mechanical stretch , GPCR , Gαq/11 , Lung development , TGFβ .

Dr. GPCR Podcast << Back to podcast list Dr. Antony A. Boucard Jr About Dr. Antony A. Boucard Jr. Dr. Richard Leduc and Dr. Dr. His lab highlighted the importance of splicing events in biasing latrophilins’ regulation of cyclic AMP

Dr. GPCR Podcast << Back to podcast list Dr. Peter Robert Banks About Dr. Peter Robert Banks Peter Banks is currently the Scientific Director at BioTek Instruments , now a part Before joining BioTek in 2008, Banks was employed by PerkinElmer for a decade. These roles included management of PerkinElmer’s BioPharma R&D program and Chair of the company’s Scientific Dr. Peter Robert Banks on the web LinkedIn Dr.