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6 items found for "DCs"
Posts (2)
- The mouse cytomegalovirus G protein-coupled receptor homolog, M33, coordinates key features of ...
The mouse cytomegalovirus (MCMV) GPCR, M33, facilitates dendritic cell (DC)-dependent viremia, the extravasation of blood-borne infected DC to the salivary gland and the frequency of reactivation events from latently-infected absence of M33 CREB Gq/11-dependent signalling correlated with reduced mobilisation of lytically-infected DC In contrast, M33ΔC38-infected DC within the vascular compartment extravasated to the salivary glands
- Neuronal Gα subunits required for the control of response to polystyrene nanoparticles in the ...
Some neuronal GPCRs (such as GTR-1, DCAR-1, DOP-2, NPR-8, NPR-12, NPR-9, and DAF-37) functioned upstream of GOA-1, some neuronal GPCRs (such as DCAR-1, DOP-2, NPR-9, NPR-8, and DAF-37) functioned upstream of GSA-1, and some neuronal GPCRs (such as DOP-2, NPR-8, DAF-37, and DCAR-1) functioned upstream of GPA
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- GPR97 depletion aggravates imiquimod-induced psoriasis pathogenesis via amplifying IL-23/IL-17 axis signal pathway
Abstract "Skin psoriasis is defined as receiving external stimulation to activate skin dendritic cells (DCs In addition, hyperproliferative keratinocytes as well as accumulation of DCs and Th17 cells were detected in imiquimod (IMQ)-induced GPR97-/- mice, which was consistent with the results in DC-cKO and K14-cKO Particularly, we found that level of NF-κB p65 was increased in GPR97-/- DCs and BDP could inhibit p65 activation in DCs.
- CCR7 acts as both a sensor and a sink for CCL19 to coordinate collective leukocyte migration
Upon exposure to the CCR7 ligand CCL19, dendritic cells (DCs) effectively internalize the receptor and This mechanism drives complex collective migration patterns, enabling DCs to create or sharpen chemotactic We further show that these self-generated gradients can sustain the long-range guidance of DCs, adapt
- The orphan G protein-coupled receptor 141 expressed in myeloid cells functions as an inflammation suppressor
Moreover, CD11c+ dendritic cells (DCs) purified from Gpr141 -/- mice increased cytokine production of